Cow's milk allergy in Thai children.

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dc.contributor.authorNgamphaiboon, Jarungchiten_US
dc.contributor.authorChatchatee, Pantipaen_US
dc.contributor.authorThongkaew, Thaneyaen_US
dc.date.accessioned2009-05-27T17:06:34Z
dc.date.available2009-05-27T17:06:34Z
dc.date.issued2008-12-26en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractCow's milk allergy (CMA) is nowadays a common problem in Thai children. We reviewed medical records of patients with CMA from the Department of Pediatrics at King Chulalongkom Memorial Hospital of the past 10 years, from 1998 to 2007. The criteria for the diagnosis of CMA included: elimination of cow's milk formula resulting in improvement of symptoms, and: recurrence of symptoms after reintroduction of cow's milk by oral challenge or by accidental ingestion. Of the 382 children with a diagnosis of CMA, 168 were girls and 214 were boys. The average age at the time of diagnosis was 14.8 months (7 days-13 years). The average duration of symptoms before diagnosis was 9.2 months. A family history of atopic diseases was found in 64.2% of the patients. All of the mothers reported an increased consumption of cow's milk during their pregnancy. The most common symptoms were respiratory (43.2%) followed by gastrointestinal (GI) (22.5%) and skin manifestations (20.1%). Less common symptoms included failure to thrive (10.9%), anemia (2.8%), delayed speech due to chronic serous otitis media (0.2%) and anaphylactic shock (0.2%). A prick skin test with cow milk extract was positive in 61.4%. Exclusively breast-fed was found in 13.2% of the patients. Successful treatment included elimination of cow's milk and milk products and substitution with soy formula in 42.5%, partial hydrolysate formula (pHF) in 35.7%, extensive hydrolysate formula (eHF) in 14.2%, and amino acid formula in 1.7%. Continued breast feeding was successful in 5.9% (with maternal restriction of cow's milk and milk products). Our study demonstrates the variety of clinical manifestations of CMA in Thai children especially respiratory symptoms which are usually overlooked.en_US
dc.description.affiliationDepartment of Pediatrics, Division of Allergy and Immunology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. ngamphaiboon_j@yahoo.comen_US
dc.identifier.citationNgamphaiboon J, Chatchatee P, Thongkaew T. Cow's milk allergy in Thai children. Asian Pacific Journal of Allergy and Immunology. 2008 Dec; 26(4): 199-204en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36470
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAnimalsen_US
dc.subject.meshBreast Feeding --epidemiologyen_US
dc.subject.meshCattleen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshMilk --immunologyen_US
dc.subject.meshMilk Hypersensitivity --diagnosisen_US
dc.subject.meshMilk Substitutesen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSkin Testsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleCow's milk allergy in Thai children.en_US
dc.typeJournal Articleen_US
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