Diagnostic accuracy of MR imaging in tuberculous spondylitis.

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dc.contributor.authorDanchaivijitr, Nasudaen_US
dc.contributor.authorTemram, Siriwanen_US
dc.contributor.authorThepmongkhol, Kullathornen_US
dc.contributor.authorChiewvit, Pipaten_US
dc.date.accessioned2009-05-27T21:39:11Z
dc.date.available2009-05-27T21:39:11Z
dc.date.issued2007-08-12en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To systemically evaluate MR imaging features of tuberculous spondylitis and to find features that may help differentiating tuberculosis from other spinal diseases. MATERIAL AND METHOD: Retrospective review of 65 MR imaging of two groups of patients between January 2002 and December 2005. Thirty-one patients were diagnosed as tuberculosis spondylitis and the rest were a randomly selected group of 34 patients with other spinal diseases. All images were reviewed by two neuroradiologists blinded to clinical data. Sensitivity and specificity of each MR imaging features were calculated. RESULTS: Three most useful MR imaging features with high sensitivity and specificity (> 80%) were endplate disruption (100%, 81.4%), paravertebral soft tissue (96.8%, 85.3%), and high signal intensity of intervertebral disc on T2W (80.6%, 82.4%). High sensitivity but low specificity signs in MRI included bone marrow edema (90.3%, 76.5%), bone marrow enhancement (100%, 42.5%), posterior element involvement (93.5%, 76.5%), canal stenosis (87.1%, 26.5%), and spinal cord or nerve root compression (80.6%, 38.2%). Low sensitivity but high specificity features in MRI were intervertebral disc enhancement (63.3%, 84.2%), vertebral collapse (58.1%, 85.3%), and kyphosis deformity (67.7%, 82.4%). Overall, the sensitivity and specificity of MRI for spinal tuberculosis were 100% and 88.2% respectively. CONCLUSION: The authors presented three good to excellent sensitivity and specificity MR imaging features for spinal tuberculosis, end plate disruption, paravertebral soft tissue formation, and high signal of intervertebral disc on T2W. In contrast to a previous study, most of the presented cases still presented with classic radiological pictures of "two vertebral disease with the destruction of the intervertebral disc". Only a small portion of the patients revealed sparing intervening disc or isolated single vertebral body involvement, which possibly reflected the early stages of the disease process.en_US
dc.description.affiliationDepartment of Radiology, Faculty of Medicine, Siriraj Hospital, 2 Prannok Rd, Bangkoknoi, Bangkok 10700, Thailand.en_US
dc.identifier.citationDanchaivijitr N, Temram S, Thepmongkhol K, Chiewvit P. Diagnostic accuracy of MR imaging in tuberculous spondylitis. Journal of the Medical Association of Thailand. 2007 Aug; 90(8): 1581-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/45165
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMagnetic Resonance Imagingen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshSpine --pathologyen_US
dc.subject.meshSpondylitis --diagnosisen_US
dc.subject.meshTuberculosis, Spinal --diagnosisen_US
dc.titleDiagnostic accuracy of MR imaging in tuberculous spondylitis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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