Frequency of Candida Infection in Post Chemotherapy Acute Leukemia Patient with Febrile Neutropenia

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dc.contributor.authorIslam, Mohammad Nazmulen_US
dc.contributor.authorIslam, Shafiqulen_US
dc.contributor.authorRehnuma, Saiqaen_US
dc.contributor.authorWasim, Mohammaden_US
dc.contributor.authorKhanam, Aklimaen_US
dc.contributor.authorAzam, Md. Shafiulen_US
dc.contributor.authorRahman, Farzanaen_US
dc.contributor.authorAziz, Mohammad Abdulen_US
dc.date.accessioned2020-09-24T07:26:49Z
dc.date.available2020-09-24T07:26:49Z
dc.date.issued2020-03
dc.description.abstractObjective: In this study our main goal is to evaluate thefrequency of candida infection in post chemotherapy febrileneutropenia patient with acute leukemia.Method: This prospective type of observation study carried outat Department of Haematology of Bangabandhu Sheikh MujibMedical University (BSMMU) from September 2016 to August2017. A total 63 patients of acute leukaemia (AML and ALL)were admitted in the Department of Haematology in BSMMU.Patients were selected by purposive sampling. A typedquestionnaire was supplied to all patients and those who gavethe written consent were selected as cases.Results: In the study, it was found that 19 (30.2%) patientsbelonged to age ≤20 years followed by 19 (30.2%) of 21-30years, 13 (20.6%) 31-40 years, 6 (9.5%) 41-50 years and 6(9.5%) >50 years of age. Immunophenotypically AML wasfound in 35 patients which was 55.6% of study population, BALL in 9 (14.3%), T ALL in 5 (7.9%) and APL in 2 (3.2%)patients. Majority of the patients 28 (44.4%) were found inconsolidation phase of chemotherapy followed by 26 (41.3%)in induction phase, 5 (7.9%) in relapse, 3 (4.8%) in re-inductionand 1 (1.6%) in palliative phase. 6 (9.5%) patients were foundpositive for throat swab for Candida in this study and bloodculture were negative for candida. Among the AML patients 4(66.7%) patients were found positive for candida in throat swaband 36 (64.3%) were found negative.Conclusion: In the study, it was found that among candida inthroat swab were more common in AML than ALL. Cause wasunknown but might be due to Reduce duration of neutropeniaby applying G-CSF and empirical local and systemic antifungaltherapy.en_US
dc.identifier.affiliationsMedical Officer, Medicine (OPD), Sylhet MAG Osmani Medical College, Sylhet, Bangladeshen_US
dc.identifier.affiliationsMedical Officer, Dept. of Haematology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladeshen_US
dc.identifier.affiliationsJunior Consultant, Upazilla Health Complex, Zakiganj, Sylhet, Bangladeshen_US
dc.identifier.affiliationsAssistant Professor, Dept. of Haematology, Dhaka Medical College Hospital, Dhaka, Bangladeshen_US
dc.identifier.affiliationsAssistant Registrar, Dept. of Haematology and BMT, Dhaka Medical College Hospital, Dhaka, Bangladeshen_US
dc.identifier.affiliationsOSD, DG Health, Bangladeshen_US
dc.identifier.affiliationsAssistant Professor, Dept. of Haematology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladeshen_US
dc.identifier.affiliationsProfessor & Chairman, Dept. of Haematology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladeshen_US
dc.identifier.citationIslam Mohammad Nazmul, Islam Shafiqul, Rehnuma Saiqa, Wasim Mohammad, Khanam Aklima, Azam Md. Shafiul, Rahman Farzana, Aziz Mohammad Abdul. Frequency of Candida Infection in Post Chemotherapy Acute Leukemia Patient with Febrile Neutropenia. International Journal of Medical Research Professionals. 2020 Mar; 6(2): 69-73en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203582
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org//10..21276/ijmrp.2020.6.2.015en_US
dc.subjectCandida Infectionen_US
dc.subjectLeukemiaen_US
dc.subjectLymphomaen_US
dc.subjectMyelodysplastic Syndrome.en_US
dc.titleFrequency of Candida Infection in Post Chemotherapy Acute Leukemia Patient with Febrile Neutropeniaen_US
dc.typeJournal Articleen_US
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