Tropical infections in the ICU.

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dc.contributor.authorKothari, Vatsal Men_US
dc.contributor.authorKarnad, Dilip Ren_US
dc.contributor.authorBichile, Lata Sen_US
dc.date.accessioned2006-04-02en_US
dc.date.accessioned2009-05-31T05:12:11Z
dc.date.available2006-04-02en_US
dc.date.available2009-05-31T05:12:11Z
dc.date.issued2006-04-02en_US
dc.description47 references.en_US
dc.description.abstractCertain arthropod-borne infections are common in tropical regions because of favorable climatic conditions. Water-borne infections like leptospirosis are common due to contamination of water especially during the monsoon floods. Infections like malaria, leptospirosis, dengue fever and typhus sometimes cause life threatening organ dysfunction and have several overlapping features. Most patients present with classicial clinical syndromes: fever and thrombocytopenia are common in dengue, malaria and leptospirosis; coagulopathy is frequent in leptospirosis and viral hepatitis. Hepatorenal syndrome is seen in leptospirosis, falciparum malaria and scrub typhus. The pulmonary renal syndrome is caused by falciparium malaria, leptospirosis, Hantavirus infection and scrub typhus. Fever with altered mental status is produced by bacterial meningitis, Japanese B encephalitis, cerebral malarial, typhoid encephalopathy and fulminant hepatic failure due to viral hepatitis. Subtle differences in features of the organ failure exist among these infections. The diagnosis in some of these diseases is made by demonstration of antibodies in serum, and these may be negative in the first week of the illness. Hence empiric therapy for more than one disorder may be justified in a small proportion of cases. In addition to specific anti-infective therapy, management of organ dysfunction includes use of mechanical ventilation, vasopressor drugs, continuous renal replacement therapy and blood products. Timely transfer of these patients to well-equipped ICUs with experience in managing these cases can considerably decrease mortality and morbidity.en_US
dc.description.affiliationMedical Intensive Care Unit, Department of Medicine, Seth GS Medical College and KEM College, Mumbai.en_US
dc.identifier.citationKothari VM, Karnad DR, Bichile LS. Tropical infections in the ICU. Journal of the Association of Physicians of India. 2006 Apr; 54(): 291-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/95383
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDengue --diagnosisen_US
dc.subject.meshEncephalitis, Japanese --diagnosisen_US
dc.subject.meshHantavirus Infections --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshInfection --epidemiologyen_US
dc.subject.meshIntensive Care Units --utilizationen_US
dc.subject.meshLeptospirosis --diagnosisen_US
dc.subject.meshMalaria, Falciparum --diagnosisen_US
dc.subject.meshTropical Climateen_US
dc.subject.meshTyphus, Epidemic Louse-Borne --diagnosisen_US
dc.subject.meshWater --parasitologyen_US
dc.subject.meshWater Microbiologyen_US
dc.titleTropical infections in the ICU.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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