A cross-sectional study of the distribution of pediatric solid tumors at an Indian tertiary cancer center

Simple item page
dc.contributor.authorQureshi, Sajid Sen_US
dc.contributor.authorBhagat, Monica Gen_US
dc.contributor.authorKembhavi, Seema Aen_US
dc.contributor.authorChinnaswamy, Girishen_US
dc.contributor.authorVora, Tusharen_US
dc.contributor.authorPrasad, Mayaen_US
dc.contributor.authorLaskar, Siddarthen_US
dc.contributor.authorKhanna, Nehalen_US
dc.contributor.authorRamadwar, Mukta Ren_US
dc.contributor.authorShah, Snehaen_US
dc.contributor.authorSalins, Navinen_US
dc.contributor.authorTalole, Sanjayen_US
dc.date.accessioned2020-01-02T06:27:58Z
dc.date.available2020-01-02T06:27:58Z
dc.date.issued2018-01
dc.description.abstractContext: Pediatric solid tumors include a heterogeneous group of tumors, and the burden of these tumors, especially from resource-challenged countries, is not well described. AIMS: The aim of this study was to describe the distribution of solid tumors in children and the treatment outcome of Wilms tumor and hepatoblastoma. Patients and Methods: All patients under 15 years of age with histologically confirmed tumors presenting at a tertiary cancer center from January 2012 to December 2016 were identified from the hospital database. Patients with lymphomas, bone, and central nervous tumors were excluded. The demographic profile including age, sex distribution, and the treatment received were recorded for all patients. Results: The mean age of the eligible 1944 patients was 5.7 years with majority (57.3%) in the 0–4 years age group. The male-to-female ratio was 1.4:1 with a male predominance in all tumors except germ cell tumors. Soft tissue tumors were the most common tumors followed by neuroblastoma and renal tumors, whereas liver tumors formed only 6.7% of all tumors. Seventy percent of the patients received treatment completely or partially at our institute, whereas 18.3% had no cancer-directed treatment. The 3-year overall survival of patients with Wilms tumor and hepatoblastoma was 85.4 and 78.5%, respectively. Conclusions: Extracranial and extraosseous pediatric solid tumors include a wide range of tumors with a predilection for male sex and children below 4 years of age. Soft tissue tumors, neuroblastoma, and renal tumors are the most common; the outcomes of Wilms tumor and hepatoblastoma are favorable.en_US
dc.identifier.affiliations5 Department of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Nuclear Medicine, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Palliative Care, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Biostatistics, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationQureshi Sajid S, Bhagat Monica G, Kembhavi Seema A, Chinnaswamy Girish, Vora Tushar, Prasad Maya, Laskar Siddarth, Khanna Nehal, Ramadwar Mukta R, Shah Sneha, Salins Navin, Talole Sanjay. A cross-sectional study of the distribution of pediatric solid tumors at an Indian tertiary cancer center. Indian Journal of Cancer. 2018 Jan; 55(1): 55-60en_US
dc.identifier.issn0019-509X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190318
dc.languageenen_US
dc.publisherIndian Cancer Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume55en_US
dc.source.urihttps://dx.doi.org//10.4103/ijc.IJC_610_17en_US
dc.titleA cross-sectional study of the distribution of pediatric solid tumors at an Indian tertiary cancer centeren_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijoc2018v55n1p55.pdf
Size:
814.53 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Cancer