Immunochemical studies in multiple myeloma.

Simple item page
dc.contributor.authorThakar, Y Sen_US
dc.contributor.authorChande, Cen_US
dc.contributor.authorPande, Sen_US
dc.contributor.authorDhanvijay, A Gen_US
dc.contributor.authorShrikhande, A Ven_US
dc.contributor.authorSaoji, A Men_US
dc.date.accessioned2009-05-28T07:19:43Z
dc.date.available2009-05-28T07:19:43Z
dc.date.issued1997-12-26en_US
dc.description.abstractThe study deals with a total of 72 patients with Plasma cell dyscrasias (PCD) selected on the basis of atypical plasmacytosis in the bone marrow aspirate and radiological evidence of osteolytic lesions. Males(48) outnumbered the females (24). Pathological fracture and paraplegia was the commonest presenting symptom encountered in 38 patients. Electrophoresis of serum for 'M' band and Immunoelectrophoretic analysis of the serum revealed IgG myeloma in 40 patients followed by, IgA myeloma(13), Light chain disease (12) and other variants in remaining seven cases. The urinary Bence Jones proteins were detected in a total of 34 cases and was frequently encountered with IgA myeloma (7 out of 13) compared with IgG myeloma (13 out of 40) when analysed in Disc electrophoresis. Kappa light chain was observed in 21 cases and lambda counterpart in nine cases without any clinical significance. One case of solitary myeloma terminated in characteristic multicentric multiple myelomatosis within a span of six months in the sequential follow up study. We recommend the triangular approach to diagnosis of paraproteinemia with a special emphasis on immunoelectrophoresis for typing multiple myeloma and allied disorders along with disc electrophoresis for the demonstration of urinary Bence Jones protein in the routine set up.en_US
dc.description.affiliationDepartment of Microbiology, Government Medical College, Nagpur, Maharashtra, India.en_US
dc.identifier.citationThakar YS, Chande C, Pande S, Dhanvijay AG, Shrikhande AV, Saoji AM. Immunochemical studies in multiple myeloma. Indian Journal of Cancer. 1997 Dec; 34(4): 151-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51204
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshBence Jones Protein --urineen_US
dc.subject.meshElectrophoresis, Discen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoelectrophoresisen_US
dc.subject.meshImmunoglobulin A --blooden_US
dc.subject.meshImmunoglobulin G --blooden_US
dc.subject.meshImmunoglobulin M --blooden_US
dc.subject.meshImmunoglobulin kappa-Chains --blooden_US
dc.subject.meshImmunoglobulin lambda-Chains --blooden_US
dc.subject.meshIndiaen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMultiple Myeloma --diagnosisen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSex Factorsen_US
dc.titleImmunochemical studies in multiple myeloma.en_US
dc.typeClinical Trialen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Cancer