Intravitreal bevacizumab for choroidal neovascular membrane associated with Best's vitelliform dystrophy.

Simple item page
dc.contributor.authorRishi, Ekta
dc.contributor.authorRishi, Pukhraj
dc.contributor.authorMahajan, Sheshadri
dc.date.accessioned2011-12-22T05:29:56Z
dc.date.available2011-12-22T05:29:56Z
dc.date.issued2010-03
dc.description.abstractBest's vitelliform macular dystrophy is a hereditary form of progressive macular dystrophy that can be complicated by choroidal neovascularization. Authors report successful treatment of choroidal neovascularization with intravitreal bevacizumab in one such eye in an ‘adult’ Indian male with visual improvement. A 23-year-old male presented with diminution of vision in the right eye for the past sixteen months. Visual acuity was 20/400 in the that eye. After three consecutive intravitreal injections of bevacizumab (1.25 mg/0.05 ml), vision improved to 20/120. Seven months following the last injection of bevacizumab, fundus appeared stable and visual acuity was maintained. No drug-related ocular or systemic side effects were encountered. To the best of our knowledge (PubMed search), this is the first report of its kind in an adult Indian patient. Intravitreal bevacizumab appears to be a promising and cost-effective modality of treatment in such eyes with potential for improvement in vision. However, a long-term follow-up is warranted.en_US
dc.identifier.citationRishi Ekta, Rishi Pukhraj, Mahajan Sheshadri. Intravitreal bevacizumab for choroidal neovascular membrane associated with Best's vitelliform dystrophy. Indian Journal of Ophthalmology. 2010 Mar; 58(2): 160-162.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/136048
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854453/en_US
dc.subjectBest's diseaseen_US
dc.subjectbevacizumaben_US
dc.subjectchoroidal neovascular membraneen_US
dc.subjectvascular endothelial growth factoren_US
dc.subjectvitelliform macular dystrophyen_US
dc.subject.meshAngiogenesis Inhibitors --administration & dosage
dc.subject.meshAntibodies, Monoclonal --administration & dosage
dc.subject.meshAntibodies, Monoclonal, Humanized
dc.subject.meshChoroidal Neovascularization --complications
dc.subject.meshChoroidal Neovascularization --drug therapy
dc.subject.meshChoroidal Neovascularization --physiopathology
dc.subject.meshHumans
dc.subject.meshInjections, Intraocular
dc.subject.meshMacular Degeneration --complications
dc.subject.meshMale
dc.subject.meshVisual Acuity
dc.subject.meshYoung Adult
dc.titleIntravitreal bevacizumab for choroidal neovascular membrane associated with Best's vitelliform dystrophy.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijo2010v58n2p160.pdf
Size:
1.79 MB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Ophthalmology