Prevention and management of acute radiation dermatitis by the topical agents : A literature review

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Date
2010-04-18
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Journal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์
Abstract
Objectives: To review historical and current published studies on prevention and management of acuteradiation dermatitis.Data sources: Research studies, Review articles, Standard text booksConclusion: The literature showed no standard recommendation for the use of specifi c topical agentsfor prevention or management of acute radiation dermatitis. The researches studied on aloe vera gel,biafi ne cream, almond ointment, chamomile cream, Thêta-Cream® and topical vitamin E creamdemonstrated negative results for prevention and reduction of radiation induced skin alteration. Someevidence suggested the use of topical steroid, topical sucralfate/ sucralfate derivatives, hyaluronic acidcream and MDS065D. However, more studies are needed to support the fi rm recommendation.
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Journal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์; Vol. 16 No. 1 January – June 2010; 27 - 40