Accuracy and utility of intraoperative squash smear cytology in neurosurgical practice

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dc.contributor.authorKhuroo, MSen_US
dc.contributor.authorHamdani, SMen_US
dc.contributor.authorAlam, SSen_US
dc.contributor.authorSahaf, BRen_US
dc.contributor.authorDar, NQen_US
dc.contributor.authorBhat, RAen_US
dc.date.accessioned2020-09-24T07:56:00Z
dc.date.available2020-09-24T07:56:00Z
dc.date.issued2019-02
dc.description.abstractBackground: Intraoperative squash smear cytology (ISSC) is a rapid and reliable diagnostic tool that provides guidance to the neurosurgeon for precise targeting of the lesion and its surgical resection. It also helps the surgeon to modify the approach at surgery at times based on the preliminary impression of the lesion on cytology. Objectives: The present study was undertaken to assess the utility of ISSC for cytomorphological diagnosis in a resource-limited setting. The accuracy of the method was assessed by correlating cytological diagnosis with histopathological diagnosis. Materials and Methods: A total of 106 cases of central nervous system (CNS) tumors were examined by squash smear technique for cytological diagnosis which were then compared with histopathological diagnosis provided on paraffin-embedded sections. Results: Cytohistological correlation was available in all the 106 cases included in the study. Of these 106 cases, 96 were concordant with the final histopathological diagnosis, while 10 were discordant. Thus, complete correlation with final histopathological diagnosis was observed in 90.56% of cases. Conclusion: Intraoperative squash smear cytology proved to be a simple, rapid, and inexpensive technique for intraoperative consultation of CNS tumors in the absence of frozen section facility.en_US
dc.identifier.affiliationsDepartment of Pathology, Government Medical College, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.affiliationsDepartment of Neurosurgery, SMHS Hospital, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, SKIMS Medical College, Bemina, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.citationKhuroo MS, Hamdani SM, Alam SS, Sahaf BR, Dar NQ, Bhat RA. Accuracy and utility of intraoperative squash smear cytology in neurosurgical practice. International Journal of Medical Science and Public Health. 2019 Feb; 8(2): 130-135en_US
dc.identifier.issn2277-338X
dc.identifier.issn2320-4664
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/205393
dc.languageenen_US
dc.publisherInternational Journal of Medical Science and Public Healthen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.5455/ijmsph.2019.1132721112018en_US
dc.subjectCentral Nervous System Tumorsen_US
dc.subjectSquash Smear Cytologyen_US
dc.subjectIntraoperative Diagnosisen_US
dc.subjectNeurosurgical Practiceen_US
dc.titleAccuracy and utility of intraoperative squash smear cytology in neurosurgical practiceen_US
dc.typeJournal Articleen_US
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