Prescription of fixed dose combination drugs for diarrhoea.

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dc.contributor.authorChakrabarti, Amiten_US
dc.date.accessioned2007-10-17en_US
dc.date.accessioned2009-05-28T09:02:30Z
dc.date.available2007-10-17en_US
dc.date.available2009-05-28T09:02:30Z
dc.date.issued2007-10-17en_US
dc.description.abstractFixed-dose combinations (FDCs) of an antiprotozoal and an antibacterial, for treatment of diarrhoea, have been available in the Indian pharmaceutical market for about a decade. There is little evidence to substantiate this combination therapy. We evaluated 2,163 physician prescriptions for diarrhoea and found that 59 per cent of prescriptions were for FDCs. This is unethical because prescribing such combinations exposes a patient to higher risks of adverse drug reactions and also increases the chances of drug resistance. Physicians' prescribing practices in India are influenced by socioeconomic factors and the pharmaceutical industry's marketing techniques that include giving incentives to physicians to prescribe certain drugs.en_US
dc.description.affiliationDepartment of pharmacology, Sikkim Manipal Institute of Medical Sciences, Fifth Mile, Tadong, Gangtok 737 102, Sikkim, India. amitchakrabarti@hotmail.comen_US
dc.identifier.citationChakrabarti A. Prescription of fixed dose combination drugs for diarrhoea. Indian Journal of Medical Ethics. 2007 Oct-Dec; 4(4): 165-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53420
dc.language.isoengen_US
dc.source.urihttps://www.issuesinmedicalethics.orgen_US
dc.subject.meshAnti-Bacterial Agents --economicsen_US
dc.subject.meshAntiprotozoal Agents --economicsen_US
dc.subject.meshCiprofloxacin --therapeutic useen_US
dc.subject.meshDiarrhea --drug therapyen_US
dc.subject.meshDrug Costsen_US
dc.subject.meshDrug Industryen_US
dc.subject.meshDrug Prescriptions --statistics & numerical dataen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshDrug Utilization Reviewen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMarketing of Health Servicesen_US
dc.subject.meshMedical Auditen_US
dc.subject.meshMetronidazole --analogs & derivativesen_US
dc.subject.meshNorfloxacin --therapeutic useen_US
dc.subject.meshPatient Selection --ethicsen_US
dc.subject.meshPhysician's Practice Patterns --ethicsen_US
dc.subject.meshSocioeconomic Factorsen_US
dc.subject.meshTinidazole --therapeutic useen_US
dc.titlePrescription of fixed dose combination drugs for diarrhoea.en_US
dc.typeJournal Articleen_US
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