Association of vitamin A, vitamin C and zinc with laryngeal cancer.

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dc.contributor.authorKapil, Uen_US
dc.contributor.authorSingh, Pen_US
dc.contributor.authorBahadur, Sen_US
dc.contributor.authorShukla, N Ken_US
dc.contributor.authorDwivedi, Sen_US
dc.contributor.authorPathak, Pen_US
dc.contributor.authorSingh, Ren_US
dc.date.accessioned2009-05-28T06:24:27Z
dc.date.available2009-05-28T06:24:27Z
dc.date.issued2003-04-13en_US
dc.description.abstractBACKGROUND: The incidence of the cancers of the oral cavity, pharynx, esophagus and larynx in different population groups of India is amongst the highest reported in Asian countries. There is evidence that high dietary carotenoids and vitamin C may possibly decrease the risk of laryngeal cancer. Limited data is available from India on the association between these micronutrients and the risk of laryngeal cancer. AIMS: To assess the levels of vitamin A, vitamin C and zinc in laryngeal cancer patients and healthy controls. SETTING AND DESIGN: A hospital based case- control study. MATERIAL AND METHODS: One hundred and fifty five laryngeal cancer patients and a control group of 155 healthy individuals constituted the study population. Individuals in the control group were individually matched with the patients for their age +/- 2 years, sex and place of residence. Venous blood was drawn from the cases and controls and estimations of vitamin A, zinc and vitamin C was done utilizing the standard procedures. STATISTICAL ANALYSIS USED: Paired 't' test to compare the mean serum levels of vitamin A and zinc and plasma vitamin C between laryngeal cancer patients and controls. Univariate logistic regression analysis to calculate the odds ratios and the confidence intervals. RESULTS: The mean serum vitamin A, zinc and plasma vitamin C levels were significantly lower in laryngeal cancer patients as compared to the controls. CONCLUSIONS: The findings of the present study indicated a strong association of these micronutrients with laryngeal cancer in the Indian population.en_US
dc.description.affiliationDepartment of Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi-110 029. India. kapilumesh@hotmail.comen_US
dc.identifier.citationKapil U, Singh P, Bahadur S, Shukla NK, Dwivedi S, Pathak P, Singh R. Association of vitamin A, vitamin C and zinc with laryngeal cancer. Indian Journal of Cancer. 2003 Apr-Jun; 40(2): 67-70en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/49789
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAscorbic Acid --blooden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitalization --statistics & numerical dataen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLaryngeal Neoplasms --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshVitamin A --blooden_US
dc.subject.meshZinc --blooden_US
dc.titleAssociation of vitamin A, vitamin C and zinc with laryngeal cancer.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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