Thyroid Profile of Patients with Non-alcoholic Fatty Liver Disease

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dc.contributor.authorPaul, Samareshen_US
dc.contributor.authorBhaumik, Pradipen_US
dc.contributor.authorSwatilekha, Bhattacharyaen_US
dc.date.accessioned2020-10-16T08:38:19Z
dc.date.available2020-10-16T08:38:19Z
dc.date.issued2020-01
dc.description.abstractIntroduction: Non-alcoholic fatty liver disease (NAFLD) is associated with various metabolic abnormalities such as obesity, insulin resistance, and dyslipidemia. The prevalence of NAFLD is increasing gradually, which may progress to non-alcoholic steatohepatitis (NASH), cirrhosis of liver, and hepatocellular carcinoma. The important association of NAFLD and metabolic disease can lead to endocrinopathy, including thyroid diseases. Methodology: Serologically diagnosed NAFLD patient was evaluated biochemically for liver function and thyroid function to evaluate any association between these two. Results: The study shows female preponderance (63.3%) NAFLD. It was observed that 77.50% were having normal transaminase level and 22.50% had raised transaminase levels (NASH). Subclinical hypothyroidism was present among 18.30%, overt hypothyroidism was 7.50%, and hyperthyroidism was 0.80%. Among the individuals with normal transaminase level, 20.50% were hypothyroid (15.10% subclinical and 5.40% overt), and persons with raised transaminase levels (NASH), 44.44% were hypothyroid (29.63% subclinical and 14.81% overt). Conclusion: This study shows that though there was a female preponderance of NAFLD, raised transaminase was more common among male and so is the hypothyroidism. This may form a matrix to the future study for cause and effect relationship of NAFLD and thyroid diseaseen_US
dc.identifier.affiliationsPost Graduate Resident, Department of Medicine, Agartala Government Medical College, Agartala, Tripura, Indiaen_US
dc.identifier.affiliationsAssociate Professor,Department of Medicine, Agartala Government Medical College, Agartala, Tripura, Indiaen_US
dc.identifier.affiliationsJunior Research Fellowships, Medical Research Center, Agartala Government Medical College, Agartala, Tripura, Indiaen_US
dc.identifier.citationPaul Samareshen_US
dc.identifier.citationBhaumik Pradipen_US
dc.identifier.citationSwatilekha Bhattacharya. Thyroid Profile of Patients with Non-alcoholic Fatty Liver Disease. International Journal of Scientific Study. 2020 Jan; 7(10): 72-75en_US
dc.identifier.issn2321-595X
dc.identifier.issn2321-6354
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/209266
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciences (IROLHS)en_US
dc.relation.issuenumber10en_US
dc.relation.volume7en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/16_ijss_jan_oa16_-_2020.pdfen_US
dc.subjectHypothyroiden_US
dc.subjectNon-alcoholic fatty liver diseaseen_US
dc.subjectSubclinical hypothyroiden_US
dc.subjectTransaminaseen_US
dc.titleThyroid Profile of Patients with Non-alcoholic Fatty Liver Diseaseen_US
dc.typeJournal Articleen_US
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