Hyperthyroid Graves’ disease after radioiodine therapy for non-toxic multinodular goiter

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dc.contributor.authorYotsapon Thewjitcharoenen_US
dc.contributor.authorThep Himathongkamen_US
dc.date.accessioned2011-02-15T08:24:37Z
dc.date.available2011-02-15T08:24:37Z
dc.date.created2008-06-22en_US
dc.date.issued2008-06-22en_US
dc.description.abstractBackground: Radioiodine treatment has been used to reduce the size of euthyroid multinodular goiter (MNG) as an alternative to surgery. Postradioiodine Graves’ disease is a rare side effect which can occur several months after radioiodine treatment for non-toxic multinodular goiter. Objective: To report two patients who developed hyperthyroid Graves’ disease after radioiodine therapy for non-toxic multinodular goiter. Methods: We report the clinical and laboratory findings of Graves’ disease which occurred after radiotherapy. The literature was reviewed for the incidence and pathogenesis of Graves’ disease after radioiodine therapy. Results: The first case describes a 39-year-old woman presented with hyperthyroidism after repeated radioiodine therapy for non-multinodular goiter. The second case describes a 45-year-old woman who presented with hyperthyroidism after the first dose of radioiodine therapy for non-multinodular goiter. Graves’ disease was confirmed in both cases by the presence of thyrotropin receptor antibody (TRAb). Both patients respond well to methimazole. Conclusion: We demonstrate the rare occurrence of Graves’ disease as the side effect of radioiodine treatment for non-toxic multinodular goiter. They highlight the importance of recognizing patients with hyperthyroidism after radioiodine treatment as they could develop hyperthyroid Graves’ disease following this treatment.en_US
dc.identifier.citationAsian Biomedicine (Research Reviews and News); Vol. 1 No. 4 December 2007; 407-410.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/129899
dc.language.isoen_USen_US
dc.publisherAsian Biomedicine (Research Reviews and News)en_US
dc.rightsAsian Biomedicine (Research Reviews and News)en_US
dc.source.urihttps://abm.digitaljournals.org/index.php/abm/article/viewFile/144/63en_US
dc.subjectGraves’ diseaseen_US
dc.subjectpostradioiodineen_US
dc.subjectnon-toxic multinodular goiteren_US
dc.titleHyperthyroid Graves’ disease after radioiodine therapy for non-toxic multinodular goiteren_US
dc.typeClinical reporten_US
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