The outcome of resurgence of diphtheria in older children in a tertiary care hospital

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dc.contributor.authorK. R., Sachinen_US
dc.contributor.authorH., Rameshen_US
dc.contributor.authorK. G., Sachinen_US
dc.contributor.authorE. S., Siddharthen_US
dc.date.accessioned2020-09-24T07:43:17Z
dc.date.available2020-09-24T07:43:17Z
dc.date.issued2019-03
dc.description.abstractBackground: Diphtheria is a fatal bacterial infection which affects the mucous membranes of oropharyngeal and nasal cavity, caused by aerobic gram-positive bacteria Corynebacterium diphtheriae. With the advent of universal immunization against diphtheria the incidence of this infectious disease has declined dramatically with few developed nations having eradicated the disease. No large outbreaks have been reported in India in recent times.Methods: In present study, authors reviewed an outbreak of diphtheria in Davangere between the months of June 2017 and July 2018. Case records of children suspected to have diphtheria, admitted to hospitals affiliated to JJM Medical College, Davangere were retrospectively analysed.Results: 15 cases were suspected to have diphtheria on clinical examination. The mean age of presentation was 7.5 years. Fever, sore throat, difficulty in swallowing, neck swelling and patch in oral cavity were the common signs and symptoms. Airway compromise, myocarditis and neurological complications were noted. Antidiphtheritic serum (ADS) was tried in all 15 cases. Case fatality rate was 40%.Conclusions: Diphtheria is a resurgent problem in India. Prompt identification and early appropriate treatment is essential to prevent morbidity and mortality. Strict adherence to the national immunisation schedule should also be emphasized.en_US
dc.identifier.affiliationsDepartment of Pediatrics, JJM Medical College, Davanagere, Karnataka, Indiaen_US
dc.identifier.citationK. R. Sachin, H. Ramesh, K. G. Sachin, E. S. Siddharth. The outcome of resurgence of diphtheria in older children in a tertiary care hospital. International Journal of Contemporary Pediatrics. 2019 Mar; 6(2): 607-610en_US
dc.identifier.issn2349-3283
dc.identifier.issn2349-3291
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203988
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3291.ijcp20190696en_US
dc.subjectAntidiphtheritic serumen_US
dc.subjectCorynebacterium diphtheriaeen_US
dc.subjectGram positiveen_US
dc.subjectMyocarditisen_US
dc.titleThe outcome of resurgence of diphtheria in older children in a tertiary care hospitalen_US
dc.typeJournal Articleen_US
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