Adjuvant therapy in invasive thymoma: an audit of cases treated over an 8 year period.

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dc.contributor.authorAgrawal, Sen_US
dc.contributor.authorDatta, N Ren_US
dc.contributor.authorMishra, S Ken_US
dc.contributor.authorKumar, Sen_US
dc.contributor.authorTandon, Ven_US
dc.contributor.authorAyyagari, Sen_US
dc.contributor.authorAgarwal, Aen_US
dc.date.accessioned2009-05-28T06:29:40Z
dc.date.available2009-05-28T06:29:40Z
dc.date.issued1999-03-16en_US
dc.description.abstractInvasive thymomas comprise 0.1%-0.2% of all malignancies in India. This report is an audit of 11 cases (10 males and 1 female) at a mean age of 36.6 years (range 25-52 years) of invasive thymoma accrued over an eight year period treated by combined modality treatment. Nine of these presented with myaesthenia gravis. All patients underwent initial surgery (3 partial and 8 total resections) and postoperative radiotherapy. Two of the three partially resected patients received one course of chemotherapy prior to radiotherapy consisting of cyclophosphamide, vincristine, procarbazine and prednisolone. At a median follow up of 28 months (range 2-87) there have been no local relapses, one distant metastasis and one death due to uncontrolled myaesthenia. The treatment strategies with invasive thymomas would depend upon the extent of resection. Postoperative radiotherapy appears to be indicated in all cases, however the role of chemotherapy may be limited to those with partial resection.en_US
dc.description.affiliationDepartment of Radiotherapy, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Utter Pradesh, India.en_US
dc.identifier.citationAgrawal S, Datta NR, Mishra SK, Kumar S, Tandon V, Ayyagari S, Agarwal A. Adjuvant therapy in invasive thymoma: an audit of cases treated over an 8 year period. Indian Journal of Cancer. 1999 Mar; 36(1): 46-56en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/49925
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAntineoplastic Agents --administration & dosageen_US
dc.subject.meshAntineoplastic Agents, Alkylating --administration & dosageen_US
dc.subject.meshAntineoplastic Agents, Hormonal --administration & dosageen_US
dc.subject.meshAntineoplastic Agents, Phytogenic --administration & dosageen_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols --therapeutic useen_US
dc.subject.meshCause of Deathen_US
dc.subject.meshCobalt Radioisotopes --therapeutic useen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshCyclophosphamide --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMaleen_US
dc.subject.meshMedical Auditen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyasthenia Gravis --etiologyen_US
dc.subject.meshNeoplasm Invasivenessen_US
dc.subject.meshPrednisolone --administration & dosageen_US
dc.subject.meshProcarbazine --administration & dosageen_US
dc.subject.meshRadiopharmaceuticals --therapeutic useen_US
dc.subject.meshThymectomyen_US
dc.subject.meshThymoma --drug therapyen_US
dc.subject.meshThymus Neoplasms --drug therapyen_US
dc.subject.meshVincristine --administration & dosageen_US
dc.titleAdjuvant therapy in invasive thymoma: an audit of cases treated over an 8 year period.en_US
dc.typeJournal Articleen_US
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