Is this Acute Manifestation of Adrenal Crisis?

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dc.contributor.authorNwaneri, Chukwuemekaen_US
dc.date.accessioned2025-06-18T10:11:58Z
dc.date.available2025-06-18T10:11:58Z
dc.date.issued2025-04
dc.description.abstractAdrenal crisis is a life threatening complication of both primary and secondary adrenocortical insufficiency. The diagnosis of adrenal crisis requires a high index of suspicion, such as circulatory collapse, refractory hypotension, and metabolic acidosis. The clinical features are because of both mineralocorticoid and glucocorticoid deficiencies. The primary and initial treatment is intravenous cortisol therapy, and saline (sometimes glucose). Case presentation was used in this 43 year old woman who presented with dizziness, anorexia, vomiting, generalized weakness, and lethargy. She had a history of recent tuberculosis infection and was commenced on antituberculosis therapy, rifampicin. Her biochemical profile was suggestive of impending adrenal crisis. Her chest X ray and computed tomography were grossly normal. The patient recovered completely and was discharged home with the resolution of her deranged metabolic and electrolyte derangements. Appropriate specialist care is vital in patients with adrenal crisis, coupled with initial aggressive fluid resuscitation and acid base balance and good intensive care.en_US
dc.identifier.affiliationsDepartment of Emergency Medicine, The Royal Shrewsbury Hospital, Shrewsbury, SY3 8XQ, UKen_US
dc.identifier.citationNwaneri Chukwuemeka. Is this Acute Manifestation of Adrenal Crisis?. Acta Medica International. 2025 Apr; 12(1): 66-71en_US
dc.identifier.issn2349-0578
dc.identifier.issn2349-0896
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/247993
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.4103/amit.amit_89_24en_US
dc.subjectAddison’s diseaseen_US
dc.subjectadrenal crisisen_US
dc.subjectadrenal insufficiencyen_US
dc.subjectadrenocortical crisisen_US
dc.subjectprimary adrenal insufficiencyen_US
dc.subjectprimary adrenocortical insufficiencyen_US
dc.titleIs this Acute Manifestation of Adrenal Crisis?en_US
dc.typeJournal Articleen_US
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