Saccharomyces boulardii CNCM I-745: An Efficient Yeast Probiotic with Unique Properties

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dc.contributor.authorRai, Aen_US
dc.contributor.authorSingh, Aen_US
dc.contributor.authorBaliyan, Aen_US
dc.contributor.authorChoudhary, DSen_US
dc.contributor.authorChoudhary, Pen_US
dc.contributor.authorChaudhary, Ren_US
dc.contributor.authorNara, Hen_US
dc.contributor.authorParakh, Pen_US
dc.contributor.authorRavindarnath, Gen_US
dc.contributor.authorRakesh, CHen_US
dc.date.accessioned2024-12-09T10:21:49Z
dc.date.available2024-12-09T10:21:49Z
dc.date.issued2024-07
dc.description.abstractObjective: Probiotics have been associated with improved health and well-being. Both bacterial and yeast probiotics can produce anti-carcinogenic, anti-oxidant, and anti-mutagenic effects that induce protection against various bacterial diseases such as diarrhoea and respiratory tract infections. Among yeasts, Saccharomyces genus is found to be effective in improving human health. Saccharomyces boulardii CNCM I-745 is classified as a probiotic with unique properties such as variability of pH over a wide range, inability to obtain antibiotic resistance genes, and the ability to attain a steady state rapidly, providing it an advantage over bacterial probiotics. It plays a significant role in preventing antibiotic-associated diarrhoea and paediatric acute gastroenteritis as compared to bacterial probiotics. Prophylactic use of S. boulardii CNCM I-745 not only showed a significant reduction in the risk of AAD as compared to controls but also restored the gut microbiota diversity. Saccharomyces boulardii CNCM I-745 was also found to be superior to Lactobacillus rhamnosus GG and four strains of Bacillus clausii in reducing the duration of diarrhoea and hospital stay in Indian children with PAGE. Saccharomyces boulardii CNCM I-745 is also recommended by several international guidelines for the management of acute diarrhoea. It is considered a safe probiotic for the prevention of gastrointestinal disorders and it is suitable for use in both children and adults.en_US
dc.identifier.affiliationsSangam Hospital, Allahabad, Uttar Pradesh Indiaen_US
dc.identifier.affiliationsDr. Amandeep Singh Children Clinic, Amritsar, Punjab, Indiaen_US
dc.identifier.affiliationsNavjeevan Child Clinic, Muzaffarnagar, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDr. Dalpat Choudhary Child Clinic, Jodhpur, Rajasthan, Indiaen_US
dc.identifier.affiliationsDr. Pankaj Choudhary Children Clinic, Mukerian, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Paediatrics, Kilkari Children’s Hospital, Khalilabad, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Paediatrics, Latha Children’s Hospital, Guntur, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Paediatrics, Newborn Child Care Clinic, Siliguri, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Paediatrics, Sri Krishna Mother and Child Hospital, Eluru, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, Ankura Hospital, Khammam, Telangana, Indiaen_US
dc.identifier.citationRai A, Singh A, Baliyan A, Choudhary DS, Choudhary P, Chaudhary R, Nara H, Parakh P, Ravindarnath G, Rakesh CH. Saccharomyces boulardii CNCM I-745: An Efficient Yeast Probiotic with Unique Properties. International Journal of Scientific Study. 2024 Jul; 12(4): 46-54en_US
dc.identifier.issn2321-6379
dc.identifier.issn2321-595X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/242598
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume12en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/05_ijss_july_24_ra05_-_2024.pdfen_US
dc.subjectAntibiotic-associated diarrhoeaen_US
dc.subjectGastrointestinal disordersen_US
dc.subjectPaediatric acute gastroenteritisen_US
dc.subjectSaccharomyces boulardii CNCM I-745en_US
dc.subjectYeast Probioticsen_US
dc.titleSaccharomyces boulardii CNCM I-745: An Efficient Yeast Probiotic with Unique Propertiesen_US
dc.typeJournal Articleen_US
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