Analysis of risk factors of low cardiac output syndrome after pericardiectomy for tuberculous constrictive pericarditis: A retrospective study

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dc.contributor.authorYan, Shuangshuangen_US
dc.contributor.authorGuo, Jingen_US
dc.contributor.authorWang, Shuzhenen_US
dc.contributor.authorZhang, Lijuanen_US
dc.contributor.authorZhang, Lien_US
dc.contributor.authorXiao, Qiuyuen_US
dc.contributor.authorLi, Qianen_US
dc.contributor.authorZhao, Zhengkaien_US
dc.contributor.authorCheng, Lijianen_US
dc.contributor.authorXiong, Fengen_US
dc.date.accessioned2025-08-13T11:15:20Z
dc.date.available2025-08-13T11:15:20Z
dc.date.issued2025-06
dc.description.abstractObjective: Low cardiac output syndrome (LCOS) is the leading cause of death after cardiac surgery. Studies have shown that 24% of postoperative mortality in patients undergoing pericardiectomy is attributed to LCOS. It is necessary to explore the risk factors of LCOS after pericardiectomy in patients with tuberculous constrictive pericarditis (CP). Methods: Patients undergoing pericardiectomy for tuberculous CP were included in the study. The personal and clinical data of these patients with LCOS and without LCOS were collected and compared. Logistic regression analyses were conducted to identify the risk factors of postoperative LCOS. ROC curve analysis was used to check the accuracy of each risk factor to predict LCOS. Results: A total of 175 patients with tuberculous CP were included in this study, of which 35 cases developed LCOS postoperatively, resulting in an incidence rate of 20%. The independent predictors of LCOS were preop- erative NYHA class III/IV, decreased left ventricular mass index (LVMI), and hypoalbuminemia in these patients (p < 0.05). When albumin (ALB) < 30.35 g/L, it had the highest diagnostic value in predicting postoperative LCOS, with sensitivity and specificity of 59.4% and 86.9%, respectively (p < 0.01). Conclusions: For patients with tuberculous CP, preoperative NYHA class III/IV, lower LVMI, and hypo- albuminemia are independent risk factors for LCOS following pericardiectomy. Clinically, these risk factors should be identified as early as possible, and early pericardiectomy should be performed when the patient’s cardiac function remains well-preserved to avoid the occurrence of cardiac cachexia, myocardial atrophy and severe hepatic insufficiency.en_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Radiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiosurgery, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.affiliationsDepartment of Cardiology, The Third People’s Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Chinaen_US
dc.identifier.citationYan Shuangshuang, Guo Jing, Wang Shuzhen, Zhang Lijuan, Zhang Li, Xiao Qiuyu, Li Qian, Zhao Zhengkai, Cheng Lijian, Xiong Feng. Analysis of risk factors of low cardiac output syndrome after pericardiectomy for tuberculous constrictive pericarditis: A retrospective study. Indian Heart Journal. 2025 Jun; 77(3): 164-169en_US
dc.identifier.issn0019-4832
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/253333
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber3en_US
dc.relation.volume77en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2025.05.006en_US
dc.subjectHypoalbuminemiaen_US
dc.subjectLow cardiac output syndromeen_US
dc.subjectMyocardial atrophyen_US
dc.subjectNYHA classen_US
dc.subjectTuberculous constrictive pericarditisen_US
dc.titleAnalysis of risk factors of low cardiac output syndrome after pericardiectomy for tuberculous constrictive pericarditis: A retrospective studyen_US
dc.typeJournal Articleen_US
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