Metal binding to pyridoxal derivatives. An NMR study of the interaction of Eu(III) with pyridoxal phosphate and pyridoxamine phosphate.
| dc.contributor.author | Rao, B N Narasinga | |
| dc.contributor.author | Ramakrishnan, C | |
| dc.contributor.author | Balaram, P | |
| dc.date.accessioned | 2015-07-17T06:13:01Z | |
| dc.date.available | 2015-07-17T06:13:01Z | |
| dc.date.issued | 1979-03 | |
| dc.description.abstract | The solution conformations of pyridoxal-5'-phosphate and pyridoxamine- 5'-phosphate have been investigated using Eu(III) as a nuclear magnetic resonance shift probe. Binding of Eu(III) to pyridoxal phosphate results in the formation of two complexes, at the phosphate group and the o-hydroxy-aldehyde moiety, which are in slow exchange on the nuclear magnetic resonance time-scale. The lanthanide-induced pseudo contact shifts calculated using the McConnell-Robertson equation (J. Chem. Soc. (1950), 22, 1561) are in good agreement with the experimentally observed values for both pyridoxal phosphate and pyridoxamine phosphate and lead to a family of closely related conformations. | en_US |
| dc.identifier.citation | Rao B N Narasinga, Ramakrishnan C, Balaram P. Metal binding to pyridoxal derivatives. An NMR study of the interaction of Eu(III) with pyridoxal phosphate and pyridoxamine phosphate. Journal of Biosciences. 1979 Mar; 1(1): 35-47. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/159922 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ias.ac.in/jarch/jbiosci/1/35-47.pdf | en_US |
| dc.subject | Conformation | en_US |
| dc.subject | lanthanide | en_US |
| dc.subject | nuclear magnetic resonance | en_US |
| dc.subject | pyridoxal-5' phosphate | en_US |
| dc.subject | pyridoxamine-5'-phosphate | en_US |
| dc.title | Metal binding to pyridoxal derivatives. An NMR study of the interaction of Eu(III) with pyridoxal phosphate and pyridoxamine phosphate. | en_US |
| dc.type | Article | en_US |