Spirometric Evaluation in Juvenile Systemic Lupus Erythematosus.
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Date
2014-11
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Abstract
Objective: Spirometric evaluation in juvenile systemic lupus erythematosus.
Methods: Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/
FVC, forced expiratory flow between 25-75% of vital capacity (FEF25-75%) and peak
expiratory flow rate (PEFR) of 21 patients with juvenile SLE (jSLE) were compared to
controls.
Result: Reduced FVC and FEF25-75% was found in 18 and 9 patients, respectively. All had
normal FEV1/FVC. None had respiratory complaint. When compared to controls, patients
had significantly reduced FVC [mean (SD):1.97 (0.56) vs 2.35 (0.60), P=0.002] and
FEF25-75% [2.19 (0.83) vs 2.63 (0.76), P=0.028] but similar FEV1/FVC [86.87(7.03) vs 86.72
(6.35), P=0.639].
Conclusion: jSLE patients had significant restrictive pattern and small airway involvement.
Description
Keywords
Pulmonary function tests, Spirometry, Systemic lupus erythematosus
Citation
Alam Md Mahboob, Sarkar Sumantra, Ghosh Parasar, Ray Biman, Mondal Rakesh. Spirometric Evaluation in Juvenile Systemic Lupus Erythematosus. Indian Pediatrics. 2014 Nov; 51(11): 909-911.