Administration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile.

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dc.contributor.authorSelvam, Sen_US
dc.contributor.authorNagini, Sen_US
dc.date.accessioned1995-07-01en_US
dc.date.accessioned2009-06-01T06:15:31Z
dc.date.available1995-07-01en_US
dc.date.available2009-06-01T06:15:31Z
dc.date.issued1995-07-01en_US
dc.description.abstractThis study was undertaken to evaluate the level of glycoproteins and sialic acid in rats fed di (2-ethylhexyl)-phthalate (DEHP) in the diet for 24 weeks. Protein-bound hexose, hexosamine and sialic acid were increased in plasma and liver of rats treated with DEHP, whereas the erythrocyte membrane showed a reduction following DEHP administration. Evaluation of glycoproteins is a useful indicator of the carcinogenic process. It is suggested that profound alterations in membrane components observed in the present study may be related to the carcinogenic potential of DEHP.en_US
dc.description.affiliationDepartment of Biochemistry, Annamalai University, Annamalainagar.en_US
dc.identifier.citationSelvam S, Nagini S. Administration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile. Indian Journal of Physiology and Pharmacology. 1995 Jul; 39(3): 252-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/107247
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDiethylhexyl Phthalate --toxicityen_US
dc.subject.meshErythrocyte Membrane --drug effectsen_US
dc.subject.meshGlycoproteins --blooden_US
dc.subject.meshHexosamines --blooden_US
dc.subject.meshHexoses --blooden_US
dc.subject.meshLiver --metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshPlasticizers --toxicityen_US
dc.subject.meshProtein Bindingen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSialic Acids --blooden_US
dc.titleAdministration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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