Administration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile.
dc.contributor.author | Selvam, S | en_US |
dc.contributor.author | Nagini, S | en_US |
dc.date.accessioned | 1995-07-01 | en_US |
dc.date.accessioned | 2009-06-01T06:15:31Z | |
dc.date.available | 1995-07-01 | en_US |
dc.date.available | 2009-06-01T06:15:31Z | |
dc.date.issued | 1995-07-01 | en_US |
dc.description.abstract | This study was undertaken to evaluate the level of glycoproteins and sialic acid in rats fed di (2-ethylhexyl)-phthalate (DEHP) in the diet for 24 weeks. Protein-bound hexose, hexosamine and sialic acid were increased in plasma and liver of rats treated with DEHP, whereas the erythrocyte membrane showed a reduction following DEHP administration. Evaluation of glycoproteins is a useful indicator of the carcinogenic process. It is suggested that profound alterations in membrane components observed in the present study may be related to the carcinogenic potential of DEHP. | en_US |
dc.description.affiliation | Department of Biochemistry, Annamalai University, Annamalainagar. | en_US |
dc.identifier.citation | Selvam S, Nagini S. Administration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile. Indian Journal of Physiology and Pharmacology. 1995 Jul; 39(3): 252-4 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/107247 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.ijpp.com | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Diethylhexyl Phthalate --toxicity | en_US |
dc.subject.mesh | Erythrocyte Membrane --drug effects | en_US |
dc.subject.mesh | Glycoproteins --blood | en_US |
dc.subject.mesh | Hexosamines --blood | en_US |
dc.subject.mesh | Hexoses --blood | en_US |
dc.subject.mesh | Liver --metabolism | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Plasticizers --toxicity | en_US |
dc.subject.mesh | Protein Binding | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, Wistar | en_US |
dc.subject.mesh | Sialic Acids --blood | en_US |
dc.title | Administration of the plasticizer di (2-ethylhexyl) phthalate alters glycoconjugate profile. | en_US |
dc.type | Comparative Study | en_US |
dc.type | Journal Article | en_US |
dc.type | Research Support, Non-U.S. Gov't | en_US |
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