Helicobacter pylori infection among type 2 diabetics: a case control study

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dc.contributor.authorAmir, Hafiz Qazi Muhammaden_US
dc.contributor.authorIkram, Omailaen_US
dc.contributor.authorZia, Muhammad Tayyaben_US
dc.contributor.authorTheba, Fareha Kashanen_US
dc.contributor.authorIkram, Nailaen_US
dc.contributor.authorTariq, Anasen_US
dc.date.accessioned2020-11-18T10:01:06Z
dc.date.available2020-11-18T10:01:06Z
dc.date.issued2020-03
dc.description.abstractBackground: Helicobacter pylori infection has been associated with hyperglycemia among type 2 diabetics. The objective of this study was to compare the H. pylori infection frequency in diabetic and non-diabetic patients.Methods: This case-control study was done at Al-Tibri Medical College and Hospital from May 2019 to August 2019. After written and informed consent, patients between 18-75 years with epigastric burning, dyspepsia, regurgitation were included and with history of eradication therapy, antibiotic or NSAID use in the last 6 months or surgery of upper GI tract months were excluded. Type 2 diabetics were placed in one group and non-diabetic individuals in another. Both groups were compared for presence of H. pylori infection. Data was analysed using SPSS. Demographic variables included age, gender and status of H. pylori infection. Quantitative data was expressed as frequency and percentages. Chi-square test was applied to test for significance keeping p-value of <0.05 statistically significant.Results: From 480 patients, 355 patients showed positive H. pylori, among them 282 were diabetic and 73 non-diabetic (p-value <0.001). Amongst the 355 diabetics, 55% were male Among 73 non-diabetics, 64% were male. All the patients in the study had dyspeptic symptoms and complained of dyspepsia, epigastric burning and regurgitation.Conclusions: A substantial relationship between H. pylori infection among type 2 diabetes mellitus patients was observed compared to non-diabetics. As a result, diabetic patients having active dyspeptic symptoms should undergo further confirmatory tests for diagnosing H. pylori infection.en_US
dc.identifier.affiliationsDepartment of Medicine, Sharif Medical and Dental College, Lahore, Punjab Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, King Edward Medical University Lahore, Punjab Pakistanen_US
dc.identifier.affiliationsDepartment of Physiology, Dow University of Health Sciences, Karachi, Sindh Pakistanen_US
dc.identifier.affiliationsDepartment of Physiology, Al Aleem Medical College, Lahore, Punjab Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Al-Tibri Medical College and Hospital, Karachi, Sindh, Pakistanen_US
dc.identifier.citationAmir Hafiz Qazi Muhammad, Ikram Omaila, Zia Muhammad Tayyab, Theba Fareha Kashan, Ikram Naila, Tariq Anas. Helicobacter pylori infection among type 2 diabetics: a case control study. International Journal of Research in Medical Sciences. 2020 Mar; 8(3): 1047-1050en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212186
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20200779en_US
dc.subjectDiabetes mellitusen_US
dc.subjectDyspepsiaen_US
dc.subjectEpigastric burningen_US
dc.subjectHelicobacter pylorien_US
dc.subjectRegurgitationen_US
dc.titleHelicobacter pylori infection among type 2 diabetics: a case control studyen_US
dc.typeJournal Articleen_US
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