Treatment of Opisthorchis viverrini and intestinal fluke infections with Praziquantel.

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dc.contributor.authorPungpak, Sen_US
dc.contributor.authorRadomyos, Pen_US
dc.contributor.authorRadomyos, B Een_US
dc.contributor.authorSchelp, F Pen_US
dc.contributor.authorJongsuksuntigul, Pen_US
dc.contributor.authorBunnag, Den_US
dc.date.accessioned2009-05-27T14:49:24Z
dc.date.available2009-05-27T14:49:24Z
dc.date.issued1998-06-14en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe study was carried out from September to November 1997 in Phrae Province of northern Thailand. A total of 95 adult patients with Opisthorchis-like ova in their stools were randomly treated with two different manufactured Praziquantels. Group 1, consisting of 49 patients, received a single dose of 40 mg per kg Praziquantel manufactured by the Thai Government Pharmaceutical Organization. Group 2 (46 patients) received Biltricide at the same dosage. Haplorchis taichui, H. yokogawai, Echinostome spp., O. viverrini, Taenia saginata and Enterobius vermicularis were expelled in the stools after treatment. Minute intestinal flukes were detected in 64% of patients. O. viverrini was found in lower proportion of 17%. By formalin-ether concentration examination one stool specimen from each patient, the cure rate in both groups on the 30th day of treatment was 100%. The side effects of the two different Praziquantel treatments were mild with no significant difference. Praziquantel, regardless of its manufacture, proved effective against O. viverrini and other minute intestinal flukes (H. taichui, H. yokogawai and Echinostome spp).en_US
dc.description.affiliationDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Bangkok, Thailand.en_US
dc.identifier.citationPungpak S, Radomyos P, Radomyos BE, Schelp FP, Jongsuksuntigul P, Bunnag D. Treatment of Opisthorchis viverrini and intestinal fluke infections with Praziquantel. The Southeast Asian Journal of Tropical Medicine and Public Health. 1998 Jun; 29(2): 246-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/31180
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/1998-29-2/1998-29-2-246.pdfen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntiplatyhelmintic Agents --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIntestinal Diseases, Parasitic --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOpisthorchiasis --drug therapyen_US
dc.subject.meshOpisthorchis --isolation & purificationen_US
dc.subject.meshPraziquantel --pharmacologyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleTreatment of Opisthorchis viverrini and intestinal fluke infections with Praziquantel.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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