Calculating prevalence of hepatitis B in India: Using population weights to look for publication bias in conventional meta-analysis.

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dc.contributor.authorBatham, Ashish
dc.contributor.authorGupta, Manoj Anand
dc.contributor.authorRastogi, Pallav
dc.contributor.authorGarg, Shubham
dc.contributor.authorSreenivas, V
dc.contributor.authorPuliyel, Jacob M
dc.date.accessioned2012-10-25T07:37:47Z
dc.date.available2012-10-25T07:37:47Z
dc.date.issued2009-12
dc.description.abstractPublication bias can result from the propensity of researchers to document what is unusual. This can distort the inferences drawn in systematic reviews. To measure the distortion, it has been suggested that a second analysis be done; using weights proportional to the size of the population from which the samples are drawn. We re-evaluate data from a published meta-analysis on prevalence of hepatitis B in India, to see how this approach alters the results. Prevalence of hepatitis B among tribal and non-tribal populations in different States was analyzed. Weights were then assigned according to population of the State. The overall country prevalence was then calculated. Using population-weights it is estimated that the point-prevalence of hepatitis B among non-tribal populations is 3.07% [95% CI: 2.5 - 3.64]. Among tribal populations it is 11.85% (CI 10.76 -12.93). Overall prevalence was 3.70 (CI: 3.17 -4.24) (corresponding to a chronic carrier rate of 2.96%). The present analysis using population-weights has resulted in the estimated prevalence among non tribal populations increasing by 24% and that among tribal populations decreasing by 25.5% when compared to figures of the metaanalysis published earlier. The advantages and drawbacks of this procedure are discussed.en_US
dc.identifier.citationBatham Ashish, Gupta Manoj Anand, Rastogi Pallav, Garg Shubham, Sreenivas V, Puliyel Jacob M. Calculating prevalence of hepatitis B in India: Using population weights to look for publication bias in conventional meta-analysis. Indian Journal of Pediatrics. 2009 Dec; 76(12): 1247-1257.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/142452
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/icb/t09/i12/icbt09i12p1247.pdfen_US
dc.subjectHepatits Ben_US
dc.subject.meshData Interpretation, Statistical
dc.subject.meshHepatitis B --ethnology
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshMeta-Analysis as Topic
dc.subject.meshPopulation Groups --statistics & numerical data
dc.subject.meshPrevalence
dc.subject.meshPublication Bias
dc.subject.meshResidence Characteristics
dc.titleCalculating prevalence of hepatitis B in India: Using population weights to look for publication bias in conventional meta-analysis.en_US
dc.typeArticleen_US
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