Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis.
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Date
2010-04
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Abstract
A low-cost method of detecting multi-drug resistant Mycobacterium tuberculosis (MDR-TB) with the possibility of quick adoption in a resource limited setting is urgently required. We conducted a study combining isoniazid and rifampicin in a single LJ medium, to detect MDR-TB strains. Combined and individual drug media showed 100% concordance for the detection of MDR-TB and susceptible strains by proportion method. Considering the results, combined isoniazid and rifampicin containing medium could be considered for use in settings where the sole detection of MDR-TB strains is justified.
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Keywords
Mycobacterium tuberculosis, MDR-TB, Isoniazid, Rifampicin, PST
Citation
Nalini S, Lakshmi R, Devika K, Ravikumar D, Ramachandran R. Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis. Indian Journal of Medical Microbiology. 2010 Apr-Jun; 28(2): 162-163.