Effect of acute ingestion of tobacco on gastric mucosa. An endoscopic study.

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dc.contributor.authorParikh, S Sen_US
dc.contributor.authorAmrapurkar, D Nen_US
dc.contributor.authorViswanath, Nen_US
dc.contributor.authorDesai, H Gen_US
dc.contributor.authorKalro, R Hen_US
dc.date.accessioned1991-07-01en_US
dc.date.accessioned2009-05-30T20:19:15Z
dc.date.available1991-07-01en_US
dc.date.available2009-05-30T20:19:15Z
dc.date.issued1991-07-01en_US
dc.description.abstractOne hundred patients with non ulcer dyspepsia with history of chronic tobacco chewing were examined endoscopically to assess the effect of tobacco ingestion on the gastric mucosa. Gastric erosions were seen in 20 patients in the fasting state. The remaining 80 patients in whom gastroscopy did not reveal erosions were subjected to repeat gastroscopy after tobacco ingestion. In 40 patients, endoscopy was repeated 30 minutes after 200 mg of tobacco ingestion (Group I) and in another 40 patients endoscopy was repeated 1 hour after 400 mg of tobacco ingestion (Group II). Eleven patients (27.5%) in Group I and 19 (47.5%) in Group II developed gastric erosions. Erosions were observed mainly along the lesser curvature, and in the fundus and the body of stomach. Gastric pH, determined after tobacco ingestion, was 2.4 +/- 0.43 in patients with erosions and 3.0 +/- 0.67 in patients without erosions. It is concluded that tobacco ingestion produces dose-dependent damage to the gastric mucosa as seen on endoscopy. Hence, history of tobacco ingestion should always be asked for in patients with gastric erosions.en_US
dc.description.affiliationDepartment of Gastroenterology, BYL Nair Charitable Hospital, Bombay.en_US
dc.identifier.citationParikh SS, Amrapurkar DN, Viswanath N, Desai HG, Kalro RH. Effect of acute ingestion of tobacco on gastric mucosa. An endoscopic study. Journal of the Association of Physicians of India. 1991 Jul; 39(7): 529-31en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/87590
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshGastric Acidity Determinationen_US
dc.subject.meshGastric Mucosa --drug effectsen_US
dc.subject.meshGastroscopyen_US
dc.subject.meshHumansen_US
dc.subject.meshPlants, Toxicen_US
dc.subject.meshStomach Diseases --chemically induceden_US
dc.subject.meshTobacco, Smokeless --adverse effectsen_US
dc.titleEffect of acute ingestion of tobacco on gastric mucosa. An endoscopic study.en_US
dc.typeJournal Articleen_US
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