A case of haloperidol induced neuroleptic malignant syndrome in postpartum psychosis: a rare case report and review of literature

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dc.contributor.authorMeganathan, Jen_US
dc.contributor.authorThirupathi, K.en_US
dc.date.accessioned2025-08-13T11:43:34Z
dc.date.available2025-08-13T11:43:34Z
dc.date.issued2025-07
dc.description.abstractNeuroleptic malignant syndrome (NMS) is a very rare and fatal complication which occurs due to use of Neuroleptic agents in the treatment of psychotic disorders. Neuroleptic drugs are assumed to be safe for both mother and foetus owing to its relative impact on untreated fulminant psychosis. NMS was observed mostly after the use of high potency first generation neuroleptic agents such as haloperidol, fluphenazine, chlorpromazine. NMS is characterised by triad of fever, muscle rigidity and altered mental status. We report a case of 26 years old G2P1L1 pregnant woman presented with abruptio placentae and intrauterine foetal demise at 35 weeks of gestation. During postpartum period, she developed NMS due to usage of haloperidol for postpartum psychosis. In this case we achieved a prompt recovery by using bromocriptine and lorazepam.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynaecology, Government Villupuram Medical College and Hospital, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynaecology, Government Villupuram Medical College and Hospital, Tamil Nadu, Indiaen_US
dc.identifier.citationMeganathan J, Thirupathi K.. A case of haloperidol induced neuroleptic malignant syndrome in postpartum psychosis: a rare case report and review of literature. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2025 Jul; 14(7): 2382-2384en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/254058
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume14en_US
dc.source.urihttps://doi.org/10.18203/2320-1770.ijrcog20251995en_US
dc.subjectNeuroleptic malignant syndromeen_US
dc.subjectAbruptio placentaeen_US
dc.subjectHyperthermiaen_US
dc.subjectCreatine phosphokinaseen_US
dc.titleA case of haloperidol induced neuroleptic malignant syndrome in postpartum psychosis: a rare case report and review of literatureen_US
dc.typeJournal Articleen_US
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