Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature

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Date
2024-06
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer – Medknow
Abstract
Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non?Hodgkin lymphoma and has a constant association with Epstein?Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero?digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22?year?old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV?encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.
Description
Keywords
Extransal NK/T cell lymphoma, gastric perforation, NK/T cell lymphoma
Citation
Mane Prashant, Ramteke Prashant, Singh Anand, Gogia Ajay, Mallick Saumyaranjan. Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature. Indian Journal of Pathology & Microbiology. 2024 Jun; 67(2): 463-465