Serological evidence of rickettsial infections in Delhi.

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dc.contributor.authorMittal, Veena
dc.contributor.authorGupta, Naveen
dc.contributor.authorBhattacharya, Dipesh
dc.contributor.authorKumar, Kaushal
dc.contributor.authorIchhpujani, R L
dc.contributor.authorSingh, Sharda
dc.contributor.authorChhabra, Mala
dc.contributor.authorRana, U V S
dc.date.accessioned2012-07-11T08:47:31Z
dc.date.available2012-07-11T08:47:31Z
dc.date.issued2012-04
dc.description.abstractBackground & objectives: Rickettsial infections remain under-diagnosed due to lack of diagnostic facilities in developing world. Here we present our experience at National Centre for Disease Control, Delhi, about a serosurvey done in Delhi for rickettsial disease with easy to perform low cost, low expertise Weil Felix test. Methods: On the basis of cut-off titre obtained in healthy population, Weil Felix test results were interpreted along with clinical data. Entomological investigation was also carried out in select areas of Delhi. Rodents were trapped from houses and gardens and vector mites were collected. Results: When serum samples were collected during initial 5 yr period from patients with fever of unknown origin, seropositivity was 8.2 per cent whereas when rickettsial infection was kept as one of the differential diagnosis by clinicians seropositivity increased to 33.3 per cent. Rickettsial infections detected were scrub typhus (48.2%) followed by spotted fever group (27.5%) and typhus group (6.8%) during 2005-2009. In preliminary entomological survey vector mite Leptotombidium deliense was found on rodents. Interpretation & conclusions: Our findings showed that results of Weil Felix test should not be disregarded, rather clinically compatible cases should be treated to save lives.en_US
dc.identifier.citationMittal Veena, Gupta Naveen, Bhattacharya Dipesh, Kumar Kaushal, Ichhpujani R L, Singh Sharda, Chhabra Mala, Rana U V S. Serological evidence of rickettsial infections in Delhi. Indian Journal of Medical Research. 2012 Apr; 135(4): 538-541.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/139427
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385240/en_US
dc.subjectDelhien_US
dc.subjectProteus vulgarisen_US
dc.subjectrickettsiaen_US
dc.subjectrodentsen_US
dc.subjectWeil Felix testen_US
dc.subject.meshHumans
dc.subject.meshIndia
dc.subject.meshProteus vulgaris
dc.subject.meshRats
dc.subject.meshRickets --diagnosis
dc.subject.meshRickets --epidemiology
dc.subject.meshRickettsia Infections --diagnosis
dc.subject.meshSerologic Tests --methods
dc.subject.meshTrombiculidae
dc.titleSerological evidence of rickettsial infections in Delhi.en_US
dc.typeArticleen_US
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