Profile of neurologic disorders associated with HIV/AIDS from Bangalore, south India (1989-96).

dc.contributor.authorSatishchandra, Pen_US
dc.contributor.authorNalini, Aen_US
dc.contributor.authorGourie-Devi, Men_US
dc.contributor.authorKhanna, Nen_US
dc.contributor.authorSantosh, Ven_US
dc.contributor.authorRavi, Ven_US
dc.contributor.authorDesai, Aen_US
dc.contributor.authorChandramuki, Aen_US
dc.contributor.authorJayakumar, P Nen_US
dc.contributor.authorShankar, S Ken_US
dc.date.accessioned2000-01-04en_US
dc.date.accessioned2009-05-27T07:10:56Z
dc.date.available2000-01-04en_US
dc.date.available2009-05-27T07:10:56Z
dc.date.issued2000-01-04en_US
dc.description.abstractOne hundred patients (95 males, 5 females, mean age at presentation 31.6 +/- 9.4 yr) with various neurological disorders associated with HIV infection during 1989-1996 were evaluated at NIMHANS, Bangalore. Eighty patients belonged to group I associated with opportunistic neuroinfections and 20 to group II--non infectious neurological disorders. Cryptococcal meningitis either alone (n = 31) or associated with tuberculous meningitis (n = 6) was the most common (46.3%) followed by neurotuberculosis either alone (n = 24) or with cerebral toxoplasmosis (n = 4) accounting for 35 per cent. Other opportunistic neuroinfections included cerebral toxoplasmosis, herpes zoster, fulminant pyogenic meningitis and neurosyphilis. Clinical characteristics, diagnostic clues, their laboratory and radiological profiles and problems encountered in diagnosis and management of these opportunistic infections are highlighted. In group II (19 males and one female; mean age of 32.6 +/- 9.4 yr), two patients had cortical dementia, three acute brain stem involvement, two epilepsy and one had features suggestive of progressive multifocal leukoencephalopathy. Two patients of group I during follow up developed cortical dementia. Six had peripheral nervous system involvement similar to Guillain-Barre syndrome. Sixty six patients (63 of group I and 3 of group II) progressed to AIDS, 33 patients from group I and one patient from group II succumbed to the disease. With the rapid increase in the incidence of HIV/AIDS and an increase in the neurological manifestations of HIV/AIDS it is important to recognise the magnitude of the problem for health planning in India.en_US
dc.description.affiliationDepartment of Neurology, National Institute of Mental Health & Neuro Sciences, Bangalore.en_US
dc.identifier.citationSatishchandra P, Nalini A, Gourie-Devi M, Khanna N, Santosh V, Ravi V, Desai A, Chandramuki A, Jayakumar PN, Shankar SK. Profile of neurologic disorders associated with HIV/AIDS from Bangalore, south India (1989-96). Indian Journal of Medical Research. 2000 Jan; 111(): 14-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19644
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAIDS-Related Opportunistic Infections --classificationen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNervous System Diseases --classificationen_US
dc.titleProfile of neurologic disorders associated with HIV/AIDS from Bangalore, south India (1989-96).en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description: