Clinical trial of albendazole in hookworm infection.

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dc.contributor.authorViravan, Cen_US
dc.contributor.authorMigasena, Sen_US
dc.contributor.authorBunnag, Den_US
dc.contributor.authorHarinasuta, Ten_US
dc.date.accessioned2009-05-27T15:44:32Z
dc.date.available2009-05-27T15:44:32Z
dc.date.issued1982-12-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractA clinical trial of albendazole (Zentel R) was carried out at the Hospital for Tropical Diseases in 1981. Thirty-five patients with hookworm infection were divided into 2 groups A, B and treated with a single dose of albendazole 400 mg and 600 mg respectively. The age of the patients ranged from 12 to 66 years and their weights ranged from 25 to 62 kilograms. Concentration and Stoll egg count methods were done at pretreatment, day 14 and day 21. At each interval two aliquots from each of the two faecal specimens were collected. The geometrical mean of EPG in Group A and B were 5406 and 5617 respectively. The cure rate in patients with less than 5000 EPG was 75% on day 21 in Group A and 67% in Group B. The mean percentage egg reduction was 95% in Group A and 99% in Group B. In patients with a higher egg out-put, the cure rate on day 21 was 50% in Group A and 29% in Group B. The mean percentage egg reduction was 91% in Group A and 93% in B. The side effects were mild and transient.en_US
dc.identifier.citationViravan C, Migasena S, Bunnag D, Harinasuta T. Clinical trial of albendazole in hookworm infection. The Southeast Asian Journal of Tropical Medicine and Public Health. 1982 Dec; 13(4): 654-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33548
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAlbendazoleen_US
dc.subject.meshBenzimidazoles --administration & dosageen_US
dc.subject.meshChilden_US
dc.subject.meshClinical Trials as Topicen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHookworm Infections --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshParasite Egg Counten_US
dc.titleClinical trial of albendazole in hookworm infection.en_US
dc.typeClinical Trialen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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