Application of whonet for the surveillance of antimicrobial resistance.

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dc.contributor.authorSharma, Aen_US
dc.contributor.authorGrover, P Sen_US
dc.date.accessioned2004-04-24en_US
dc.date.accessioned2009-05-28T09:17:02Z
dc.date.available2004-04-24en_US
dc.date.available2009-05-28T09:17:02Z
dc.date.issued2004-04-24en_US
dc.description.abstractWorld over antimicrobial resistance is a major public health problem. The WHONET software program puts each laboratory data into a common code and file format, which can be merged for national or global collaboration of antimicrobial resistance surveillance. In this study, antimicrobial sensitivity of 4,289 bacterial isolates was studied by Kirby-Bauer disk diffusion method. -lactamase production was assessed by iodometric test method. Extended spectrum -lactamase (ESBLs) were screened by ceftazidime disk sensitivity. Drug resistance was high in most of the isolates. It was maximum (80-94%) for ampicillin, nalidixic acid and cotrimoxazole. It varied between 40-60% for gentamicin, clindamycin, fluoroquinolones and coamoxyclav. It ranged from 21 to 38% for amikacin and third generation cephalosporins. Constitutive -lactamase production was highest in S.aureus (28.9%) and ESBL production was maximum in Klebsiella spp. (53.6%). WHONET software has in-built analysis program which helps in forming hospital drug policy, identification of hospital outbreaks and recognition of quality control problems in the laboratory.en_US
dc.description.affiliationDepartment of Microbiology, Indira Gandhi Medical College, Shimla - 171 001, Himachal Pradesh, India.en_US
dc.identifier.citationSharma A, Grover PS. Application of whonet for the surveillance of antimicrobial resistance. Indian Journal of Medical Microbiology. 2004 Apr-Jun; 22(2): 115-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53699
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.titleApplication of whonet for the surveillance of antimicrobial resistance.en_US
dc.typeJournal Articleen_US
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