The correlation between thrombopoietin and platelet count in adult dengue viral infection patients.

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dc.contributor.authorMatondang, Asnath Veraen_US
dc.contributor.authorWidodo, Djokoen_US
dc.contributor.authorZulkarnain, Iskandaren_US
dc.contributor.authorRengganis, Irisen_US
dc.contributor.authorTrihandini, Indangen_US
dc.contributor.authorInada, Katsuyaen_US
dc.contributor.authorEndo, Shigeatsuen_US
dc.contributor.author,en_US
dc.date.accessioned2004-04-28en_US
dc.date.accessioned2009-05-28T04:33:48Z
dc.date.available2004-04-28en_US
dc.date.available2009-05-28T04:33:48Z
dc.date.issued2004-04-28en_US
dc.description.abstractAIM: To investigate alteration in humoral regulation during the course of dengue viral infection. METHODS: A prospective analytic study had been conducted involving 40 subjects with dengue viral infection. Subjects were recruited according to consecutive non-probability sampling. Subjects were categorized according to days of illness, platelet counts and serum thrombopoietin (TPO) levels. The plasma TPO levels examinations were done once daily until the platelet counts reached more than 100,000/mm(3). RESULTS: Statistical analysis showed the mean serum TPO levels were increased during thrombocytopenia phase of the disease, and differ significantly from the convalescent phase (mean value 428 pg/ml vs 220.1 pg/ml, p= 0.00). There was also a statistically significant inverse correlation between serum TPO levels and platelet counts (p= 0.00). CONCLUSION: TPO levels were significantly increased in adult patients with dengue infection in which platelets in circulation were markedly reduced, and the TPO levels were inversely related to the platelet counts.en_US
dc.description.affiliationDepartment of Internal Medicine, Faculty of Medicine, University of Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta.en_US
dc.identifier.citationMatondang AV, Widodo D, Zulkarnain I, Rengganis I, Trihandini I, Inada K, Endo S, . The correlation between thrombopoietin and platelet count in adult dengue viral infection patients. Acta Medica Indonesiana. 2004 Apr-Jun; 36(2): 62-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/47076
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshDengue --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPlatelet Counten_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshThrombopoietin --blooden_US
dc.titleThe correlation between thrombopoietin and platelet count in adult dengue viral infection patients.en_US
dc.typeJournal Articleen_US
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