Efficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand.

Simple item page
dc.contributor.authorWanichwecha-Rungruang, Boonsongen_US
dc.contributor.authorIemsomboon, Wallopen_US
dc.date.accessioned2009-05-27T20:33:03Z
dc.date.available2009-05-27T20:33:03Z
dc.date.issued2005-09-16en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe authors evaluated the effectiveness and safety of bimatoprost using an open-label, non-comparative, three-month, community-based surveillance study. Patients (n = 458) with open-angle glaucoma or ocular hypertension received bimatoprost 0.03% ophthalmic solution as monotherapy, replacement therapy or adjunctive therapy. Bimatoprost produced a rapid, significant (p < 0.0001) reduction in intraocular pressure: monotherapy (34.6% reduction), replacement therapy (16.4% reduction); adjunctive therapy (24.1% reduction). Bimatoprost enabled more patients to achieve their pre-defined target intraocular pressure (p < 0.0001), compared to previous treatments, and significantly lowered intraocular pressure, regardless of the patients' baseline pressure level or history of pressure control. Bimatoprost was well-tolerated; the most commonly reported adverse event was conjunctival hyperaemia (19.9%). Most patients and ophthalmologists rated bimatoprost highly, compared to previously used treatments. The authors concluded that bimatoprost is an effective, well-tolerated treatment for lowering intraocular pressure in Thai patients with open-angle glaucoma or ocular hypertension.en_US
dc.description.affiliationGlaucoma Services, Department of Ophthalmology, Institute of Undergraduate Medical Education, Bangkok 10400, Thailand. boonsongw@yahoo.comen_US
dc.identifier.citationWanichwecha-Rungruang B, Iemsomboon W. Efficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand. Journal of the Medical Association of Thailand. 2005 Sep; 88(9): 1228-35en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43202
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAmidesen_US
dc.subject.meshAntihypertensive Agents --administration & dosageen_US
dc.subject.meshCloprostenol --analogs & derivativesen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Open-Angle --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshLipids --administration & dosageen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOcular Hypertension --drug therapyen_US
dc.subject.meshOphthalmic Solutions --adverse effectsen_US
dc.subject.meshPatient Satisfactionen_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshSafetyen_US
dc.subject.meshThailanden_US
dc.subject.meshTreatment Outcomeen_US
dc.titleEfficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand.en_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of the Medical Association of Thailand