Efficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand.
dc.contributor.author | Wanichwecha-Rungruang, Boonsong | en_US |
dc.contributor.author | Iemsomboon, Wallop | en_US |
dc.date.accessioned | 2009-05-27T20:33:03Z | |
dc.date.available | 2009-05-27T20:33:03Z | |
dc.date.issued | 2005-09-16 | en_US |
dc.description | Chotmaihet Thangphaet. | en_US |
dc.description.abstract | The authors evaluated the effectiveness and safety of bimatoprost using an open-label, non-comparative, three-month, community-based surveillance study. Patients (n = 458) with open-angle glaucoma or ocular hypertension received bimatoprost 0.03% ophthalmic solution as monotherapy, replacement therapy or adjunctive therapy. Bimatoprost produced a rapid, significant (p < 0.0001) reduction in intraocular pressure: monotherapy (34.6% reduction), replacement therapy (16.4% reduction); adjunctive therapy (24.1% reduction). Bimatoprost enabled more patients to achieve their pre-defined target intraocular pressure (p < 0.0001), compared to previous treatments, and significantly lowered intraocular pressure, regardless of the patients' baseline pressure level or history of pressure control. Bimatoprost was well-tolerated; the most commonly reported adverse event was conjunctival hyperaemia (19.9%). Most patients and ophthalmologists rated bimatoprost highly, compared to previously used treatments. The authors concluded that bimatoprost is an effective, well-tolerated treatment for lowering intraocular pressure in Thai patients with open-angle glaucoma or ocular hypertension. | en_US |
dc.description.affiliation | Glaucoma Services, Department of Ophthalmology, Institute of Undergraduate Medical Education, Bangkok 10400, Thailand. boonsongw@yahoo.com | en_US |
dc.identifier.citation | Wanichwecha-Rungruang B, Iemsomboon W. Efficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand. Journal of the Medical Association of Thailand. 2005 Sep; 88(9): 1228-35 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/43202 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.mat.or.th/journal/all.php | en_US |
dc.subject.mesh | Amides | en_US |
dc.subject.mesh | Antihypertensive Agents --administration & dosage | en_US |
dc.subject.mesh | Cloprostenol --analogs & derivatives | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Glaucoma, Open-Angle --drug therapy | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Lipids --administration & dosage | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Ocular Hypertension --drug therapy | en_US |
dc.subject.mesh | Ophthalmic Solutions --adverse effects | en_US |
dc.subject.mesh | Patient Satisfaction | en_US |
dc.subject.mesh | Population Surveillance | en_US |
dc.subject.mesh | Safety | en_US |
dc.subject.mesh | Thailand | en_US |
dc.subject.mesh | Treatment Outcome | en_US |
dc.title | Efficacy and safety of bimatoprost for the treatment of open-angle glaucoma and ocular hypertension: a three-month, open-label study in community-based practices in Thailand. | en_US |
dc.type | Journal Article | en_US |
dc.type | Multicenter Study | en_US |
dc.type | Research Support, Non-U.S. Gov't | en_US |
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