Nerve conduction study in young children suffering from cerebral palsy

Simple item page
dc.contributor.authorBasak, Indranien_US
dc.contributor.authorPandey, Ratnaen_US
dc.contributor.authorTiwari, Anil Kumaren_US
dc.contributor.authorPrasad, Rajnitien_US
dc.contributor.authorMandal, Maloy B.en_US
dc.contributor.authorBhagat, Priyankaen_US
dc.contributor.authorSingh, Tej Balien_US
dc.date.accessioned2023-08-19T04:57:23Z
dc.date.available2023-08-19T04:57:23Z
dc.date.issued2023-06
dc.description.abstractObjectives: Cerebral palsy (CP) is a motor impairment syndrome leading to disorders of movement and posture. Screening of electrophysiological parameters Hoffman reflex (H-reflex and nerve conduction velocities) becomes a necessary for the early detection and management of the disease. The study aimed to assess the various electrophysiological parameters of nerve conduction velocity in CP and age-matched normal children. Matrials and Methods: The present cross-sectional study was performed between children suffering from CP and healthy control. A total of 27 children of 12–24 months of age of either sex were examined. Among them, six children were normal (with age match), seven were diagnosed with spastic CP and remaining 14 children were diagnosed with hypotonic CP The electrophysiological parameters were recorded in the right lower limb (posterior tibial nerve-soleus muscle) of all children. Results: In electrophysiological parameters, H-reflex latency in secs values was significantly decreased in all CP children. The maximum amplitudes of reflexly excitable motor neurons (Hmax) (mV) and Hmax/maximum amplitude of motor response ratio in the gastrocnemius-soleus muscle were significantly increased in spastic CPas compared to control. H-reflex conduction velocity (HRCV) was significantly higher than motor nerve conduction velocity (MNCV) in hypotonic CP children. Conclusion: The electrophysiological parameters were altered in spastic CP children. The electrophysiological parameters in hypotonic CP were within range, indicating they did not suppress the neuronal motor pool. However, HRCV was significantly more than MNCV in hypotonic CP, suggesting some myelination process defect/white matter injury in motor neurons. We concluded that the electrophysiological parameters of the nerve conduction study are a reliable test for the assessment of tone of muscles in children. Thus, it may help in the early initiation of the treatment and therapies in CP children.en_US
dc.identifier.affiliationsDepartment of Physiology, ESIC Medical College and Hospital, Alwar, Rajasthan, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Biostatistics, Centre of Biostatistics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, Indiaen_US
dc.identifier.citationBasak Indrani, Pandey Ratna, Tiwari Anil Kumar, Prasad Rajniti, Mandal Maloy B., Bhagat Priyanka, Singh Tej Bali. Nerve conduction study in young children suffering from cerebral palsy. Indian Journal of Physiology and Pharmacology. 2023 Jun; 67(2): 118-124en_US
dc.identifier.issn0019-5499
dc.identifier.issn2582-2799
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223987
dc.languageenen_US
dc.publisherScientific Scholar on behalf of Association of Physiologists and Pharmacologists of Indiaen_US
dc.relation.issuenumber2en_US
dc.relation.volume67en_US
dc.source.urihttps://doi.org/10.25259/IJPP_423_2022en_US
dc.subjectHoffman reflexen_US
dc.subjectMotor nerve conduction velocityen_US
dc.subjectHoffman reflex conduction velocityen_US
dc.subjectCerebral palsyen_US
dc.titleNerve conduction study in young children suffering from cerebral palsyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IJPP2023v67n2p118.pdf
Size:
928.58 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Physiology and Pharmacology