A Dedifferentiated Solitary Fibrous Tumor in Mesentry with Osteosarcomatous Differentiation

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dc.contributor.authorGangoli, Aparnaen_US
dc.contributor.authorGhosh, Triparnaen_US
dc.contributor.authorChippalkatti, Komal Den_US
dc.contributor.authorKulgod, Sanjeeven_US
dc.date.accessioned2024-09-24T07:12:12Z
dc.date.available2024-09-24T07:12:12Z
dc.date.issued2023-08
dc.description.abstractIntroduction: Solitary fibrous tumor, a mesenchymal neoplasm, was initially observed in pleura. Though they were later found in many extra pleural sites. It rarely occurs in mesentery. The biology of solitary fibrous tumor is unpredictable, it ranges from benign to overtly malignant. Dedifferentiation, a phenomenon which is morphologically characterized by abrupt transition between the well differentiated component and high-grade areas of tumor, is well described in soft tissue and bone tumors. However, dedifferentiation within solitary fibrous tumor is a rare phenomenon. Case report: We report a case of dedifferentiated solitary fibrous tumor arising in mesentery. Computed tomography revealed a large well-lobulated heterogeneously enhanced solid necrotic mass lesion involving the pelvic abdomen. Macroscopically, the resected tumor was 24 x 20 x 10 cm. microscopic examination revealed a malignant spindle cell tumor juxtaposed with osteosarcomatous component. The spindle cell component showed diffuse expression of SMA, CD34 & STAT6. The osteosarcomatous component showed diffuse expression of SATB2. Conclusion: This is a rare case of mesenteric dedifferentiated solitary fibrous tumor with osteosarcomatous differentiation.en_US
dc.identifier.affiliationsHOD, Department of Pathology, Cytecare Cancer Hospital, Bangalore, Karnataka-560064en_US
dc.identifier.affiliationsFellow-tumor Pathology, Department of Pathology, Cytecare Cancer Hospital, Bangalore, Karnataka-560064en_US
dc.identifier.affiliationsConsultant Pathologist, Department of Pathology, Cytecare Cancer Hospital, Bangalore, Karnataka-560064en_US
dc.identifier.affiliationsConsultant Oncosurgeon, Department of Oncosurgery, Radon Cancer Centre, Hubli, Karnataka-580021, Indiaen_US
dc.identifier.citationGangoli Aparna, Ghosh Triparna, Chippalkatti Komal D, Kulgod Sanjeev. A Dedifferentiated Solitary Fibrous Tumor in Mesentry with Osteosarcomatous Differentiation . International Journal of Contemporary Medical Research. 2023 Aug; 10(8): 1-4en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/228169
dc.languageenen_US
dc.publisherInternational Journal of Contemporary Medical Researchen_US
dc.relation.issuenumber8en_US
dc.relation.volume10en_US
dc.source.urihttps://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_3722.pdfen_US
dc.subjectDedifferentiated Solitary Fibrous Tumoren_US
dc.subjectMesentryen_US
dc.titleA Dedifferentiated Solitary Fibrous Tumor in Mesentry with Osteosarcomatous Differentiationen_US
dc.typeJournal Articleen_US
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