Bone metastasis in hepatocellular carcinoma: need for reappraisal of treatment.

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dc.contributor.authorAttili, V Satya Sureshen_US
dc.contributor.authorBabu, K Govinden_US
dc.contributor.authorLokanatha, Den_US
dc.contributor.authorBapsy, P Pen_US
dc.contributor.authorRamachandra, Cen_US
dc.contributor.authorRajshekar, Hen_US
dc.date.accessioned2008-04-09en_US
dc.date.accessioned2009-06-01T16:15:40Z
dc.date.available2008-04-09en_US
dc.date.available2009-06-01T16:15:40Z
dc.date.issued2008-04-09en_US
dc.description.abstractBone is an uncommon site of metastasis in patients with hepatocellular carcinoma (HCC), and often overlooked. We report two cases that had isolated bone metastasis; one of them had prolonged disease-free survival. The present series, along with the literature review, reinforces the idea that HCC should be considered in the differential diagnoses in patients presenting with metastases in bone. The presence of isolated bone metastases need not necessarily indicate poor prognosis, and all such patients need to be offered chemotherapy and at least one of the bone-directed therapies (either local radiation in cases of localized disease or bisphosphonates in the presence of extensive disease) as they may have a better outcome with therapy.en_US
dc.description.affiliationDepartment of Medical Oncology, Kidwai Memorial Institute of Oncology, Dr. M.H. Marigowda Road, Bangalore-560029, India. sureshattili@yahoo.comen_US
dc.identifier.citationAttili VS, Babu KG, Lokanatha D, Bapsy PP, Ramachandra C, Rajshekar H. Bone metastasis in hepatocellular carcinoma: need for reappraisal of treatment. Journal of Cancer Research and Therapeutics. 2008 Apr-Jun; 4(2): 93-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/111423
dc.language.isoengen_US
dc.source.urihttps://www.cancerjournal.neten_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols --therapeutic useen_US
dc.subject.meshBone Neoplasms --drug therapyen_US
dc.subject.meshBrain Neoplasms --diagnosisen_US
dc.subject.meshCarcinoma, Hepatocellular --drug therapyen_US
dc.subject.meshCisplatin --administration & dosageen_US
dc.subject.meshDiphosphonates --administration & dosageen_US
dc.subject.meshDoxorubicin --administration & dosageen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImidazoles --administration & dosageen_US
dc.subject.meshLiver Neoplasms --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPalliative Careen_US
dc.subject.meshRadiography, Thoracicen_US
dc.titleBone metastasis in hepatocellular carcinoma: need for reappraisal of treatment.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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