Aetiological spectrum of chronic liver disease in eastern India.

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dc.contributor.authorRay, Gen_US
dc.contributor.authorGhoshal, U Cen_US
dc.contributor.authorBanerjee, P Ken_US
dc.contributor.authorPal, B Ben_US
dc.contributor.authorDhar, Ken_US
dc.contributor.authorPal, A Ken_US
dc.contributor.authorBiswas, P Ken_US
dc.date.accessioned2000-04-06en_US
dc.date.accessioned2009-06-04T03:46:07Z
dc.date.available2000-04-06en_US
dc.date.available2009-06-04T03:46:07Z
dc.date.issued2000-04-06en_US
dc.description.abstractAIM: To evaluate the aetiologic spectrum of chronic liver disease (CLD) in a tertiary referral center in Eastern India. METHODS: A total of 175 patients (cirrhosis 166, chronic hepatitis 9) diagnosed by clinical, biochemical, radiological and histopathological (42 cases) parameters were evaluated for aetiology. Investigations included: HBsAg and anti HCV (third generation) by ELISA. HBeAg and HBV DNA were tested in HBsAg positive patients. HCV RNA was tested in anti-HCV positive patients. Markers for autoimmune and Wilson's disease (anti-nuclear antibody, anti smooth muscle antibody, serum ceruloplasmin, urinary copper and slit lamp examination for KF ring) were done where clinically indicated. RESULTS: A total of 62 (35.4%) patients had HBV related CLD and 6 (9.7%) of them had pre-core mutant. HCV was present in 17/114 (14.9%) cases and none had infection with both viruses. Autoimmunity, Wilson's disease and alcohol were the aetiological factors in 5 (2.8%), 5 (2.8%) and 3 (1.7%) patients respectively. No aetilogy could be found in 18/114 (15.8%) patients. CONCLUSIONS: It is concluded that HBV is the commonest cause of CLD in Eastern India. Alcohol and HCV are uncommon in this part of the country.en_US
dc.description.affiliationDepartment of Gastroenterology, Institute of Postgraduate Medical Education & Research, Calcutta.en_US
dc.identifier.citationRay G, Ghoshal UC, Banerjee PK, Pal BB, Dhar K, Pal AK, Biswas PK. Aetiological spectrum of chronic liver disease in eastern India. Tropical Gastroenterology. 2000 Apr-Jun; 21(2): 60-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/124489
dc.language.isoengen_US
dc.source.urihttps://www.tropicalgastro.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis B --complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLiver Diseases --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.titleAetiological spectrum of chronic liver disease in eastern India.en_US
dc.typeJournal Articleen_US
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