Somatostatin receptor tumor imaging (Tc 99m P829) in pituitary adenoma.

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dc.contributor.authorChiewvit, Sen_US
dc.contributor.authorChiewvit, Pen_US
dc.contributor.authorPusuwan, Pen_US
dc.contributor.authorSriussadaporn, Sen_US
dc.contributor.authorRatanamart, Ven_US
dc.date.accessioned2009-05-27T20:34:08Z
dc.date.available2009-05-27T20:34:08Z
dc.date.issued1999-12-05en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractTechnetium 99m P829 (99mTc P829) is a somatostatin like structure labelled with Technetium-99m. Somatostatin receptor positive tumors such as pituitary tumors, neuroendocrine tumors, and lymphomas show positive scintigraphy. Eleven patients suspected of having a pituitary mass (12 studies) were studied with 99mTc P829. Three pituitary adenoma patients (4 studies) showed positive somatostatin receptor tumor imaging. Eight negative somatostatin receptor scintigraphy were one hypothyroid induced pituitary hyperplasia, one craniopharyngioma, one normal pituitary tissue with focal hyperplasia, one ACTH secreting pituitary tumor, one GH, PRL secreting pituitary tumor post transphenoidal partial tumor removal, and no surgery in 3 patients. Finally, somatostatin receptor imaging may be useful as a tumor localizing technique in addition to conventional CT and MRI imaging and identify patients who might potentially benefit from octreotide treatment. In addition, the development of peptide analogs coupling to beta-emitting radiopharmaceutical may lead to a situation in which diagnosis peptide receptor scintigraphy can be followed by radionuclide therapy.en_US
dc.description.affiliationDepartment of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationChiewvit S, Chiewvit P, Pusuwan P, Sriussadaporn S, Ratanamart V. Somatostatin receptor tumor imaging (Tc 99m P829) in pituitary adenoma. Journal of the Medical Association of Thailand. 1999 Dec; 82(12): 1208-13en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43235
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdenoma --radionuclide imagingen_US
dc.subject.meshAdulten_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPituitary Neoplasms --radionuclide imagingen_US
dc.subject.meshReceptors, Somatostatinen_US
dc.subject.meshTechnetium Compounds --diagnostic useen_US
dc.subject.meshTomography, Emission-Computed, Single-Photonen_US
dc.titleSomatostatin receptor tumor imaging (Tc 99m P829) in pituitary adenoma.en_US
dc.typeJournal Articleen_US
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