The levels of cockroach allergen in relation to cockroach species and allergic diseases in Thai patients.

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dc.contributor.authorTungtrongchitr, Anchaleeen_US
dc.contributor.authorSookrung, Nitaten_US
dc.contributor.authorMunkong, Nantiyaen_US
dc.contributor.authorMahakittikun, Vannaen_US
dc.contributor.authorChinabut, Pisithen_US
dc.contributor.authorChaicumpa, Wanpenen_US
dc.contributor.authorBunnag, Chaweewanen_US
dc.contributor.authorVichyanond, Pakiten_US
dc.date.accessioned2009-05-27T17:27:39Z
dc.date.available2009-05-27T17:27:39Z
dc.date.issued2004-12-30en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractRecently, cockroaches have been established as the second most Important allergen, producing allergic diseases, especially in low socioeconomic populations. In Thailand, about 44-61% of atopic patients were positive to cockroach extract by a skin-prick test. This study examined cockroach allergen levels in relation to cockroach species and allergic diseases in the houses of cockroach-sensitive patients. Sixty households of allergic patients in the Bangkok metropolitan area were surveyed using open- and closed-ended questionnaires. Cockroaches were collected using commercial cockroach traps, while dust samples were obtained from the bedrooms, kitchens and living rooms of the houses using a vacuum cleaner. The cockroaches were counted and their species Identified. The levels of cockroach allergens were determined by specific monoclonal antibodies using a monoclonal antibody-polyclonal antibody based sandwich ELISA kit. Six cockroach species were Identified: Periplaneta americana (American cockroach, 72.15%), Supella longlpalpa (2.75%, found in only one house), Periplaneta brunnea (0.78%), Periplaneta australaslae (0.78%), Neostylopyga rhombifolla (0.78%), Blattella germanica (German cockroach, 0.39%) and nymphs (22.35%). Allergens of the predominant species, P. americana, were detectable in all homes studied, with the highest levels in the kitchen areas. The range of allergen levels in house dust varied from 0.40-162.00 microg per g of dust. The median and mean allergen levels in kitchen dust were 59.16 microg and 62.80 microg per g of dust, respectively, while the median allergen level in bedroom dust was only 15.90 microg per g of dust. The German cockroach allergen (Bla g 2) was undetectable in any of the houses. IN CONCLUSION: P. americana was the most common cockroach and may be the species causing allergic diseases, especially asthma, in Thailand, which differs from the USA and Europeen_US
dc.description.affiliationDepartment of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationTungtrongchitr A, Sookrung N, Munkong N, Mahakittikun V, Chinabut P, Chaicumpa W, Bunnag C, Vichyanond P. The levels of cockroach allergen in relation to cockroach species and allergic diseases in Thai patients. Asian Pacific Journal of Allergy and Immunology. 2004 Jun-Sep; 22(2-3): 115-21en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37241
dc.language.isoengen_US
dc.subject.meshAllergens --analysisen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCockroaches --classificationen_US
dc.subject.meshDust --immunologyen_US
dc.subject.meshEnvironmental Exposure --adverse effectsen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshHumansen_US
dc.subject.meshHypersensitivity --epidemiologyen_US
dc.subject.meshInsect Proteins --analysisen_US
dc.subject.meshThailanden_US
dc.titleThe levels of cockroach allergen in relation to cockroach species and allergic diseases in Thai patients.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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