Four percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practice

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dc.contributor.authorSharma, Brijen_US
dc.contributor.authorGupta, Manishen_US
dc.contributor.authorSharma, Rajeshen_US
dc.contributor.authorGupta, Ankuren_US
dc.contributor.authorSharma, Neetuen_US
dc.contributor.authorSharma, Mukeshen_US
dc.contributor.authorSharma, Vineetaen_US
dc.contributor.authorSiddharth Vatsen_US
dc.contributor.authorGupta, Manojen_US
dc.contributor.authorSeam, Rajeev Kumaren_US
dc.date.accessioned2020-11-18T10:07:24Z
dc.date.available2020-11-18T10:07:24Z
dc.date.issued2019-01
dc.description.abstractContext: Radiotherapy is a very effective treatment modality for pelvic malignancies such as carcinoma of the cervix. However, it is quite common for chronic radiation proctitis (CRP) to manifest after radical radiotherapy. CRP is a source of significant morbidity, and there is a lack of effective treatment modalities. There also exists a general lack of guidelines on management of CRP. Aims: To assess the benefit from 4% formalin application for the treatment of Grade >2 CRP among patients previously treated with radical radiotherapy for cervical carcinoma. Settings and Design: This retrospective descriptive study involved 29 eligible patients who were treated from November 2010 - November 2015 for CRP with 4% formalin application. Materials and Methods: Of the 1864 patients of carcinoma cervix treated during the said patients, 29 patients fulfilled the eligibility criteria. Eligible patients were invited telephonically for follow-up and were assessed for response and complications of the procedure. Results: The treatment of hemorrhagic radiation proctitis with local formalin instillation is effective, well tolerated and safe procedure. The procedure is inexpensive, technically simple and can be done on an outpatient basis. 62% patients had complete freedom from rectal bleed, while 34.5% patients had partial benefit. Only one patient required diversion colostomy for persistent bleeding.en_US
dc.identifier.affiliationsDepartment of Gastroenterology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiotherapy, Cancer Hospital, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Gastroenterology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Anatomy, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Physiology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiotherapy, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiotherapy, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiotherapy, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Radiotherapy, IGMC, Shimla, Himachal Pradesh, Indiaen_US
dc.identifier.citationSharma Brij, Gupta Manish, Sharma Rajesh, Gupta Ankur, Sharma Neetu, Sharma Mukesh, Sharma Vineeta, Siddharth Vats, Gupta Manoj, Seam Rajeev Kumar. Four percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practice. Journal of Cancer Research and Therapeutics. 2019 Jan; 15(1): 92-95en_US
dc.identifier.issn0973-1482
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213455
dc.languageenen_US
dc.publisherWolters Kluwer India Pvt. Ltd.en_US
dc.relation.issuenumber1en_US
dc.relation.volume15en_US
dc.source.urihttps://dx.doi.org//10.4103/jcrt.JCRT_393_17en_US
dc.subject4% formalinen_US
dc.subjectcarcinoma cervixen_US
dc.subjectradiation proctitisen_US
dc.titleFour percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practiceen_US
dc.typeJournal Articleen_US
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