Pulmonary Mycobacterium kyorinense disease: A case report and review of literature

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dc.contributor.authorSaranathan, Ren_US
dc.contributor.authorPadmapriyadarsini, Cen_US
dc.contributor.authorSivaramakrishnan, GNen_US
dc.contributor.authorPerumal, BKen_US
dc.contributor.authorKannayan, Sen_US
dc.contributor.authorJoseph, Ben_US
dc.contributor.authorGopalan, Nen_US
dc.contributor.authorHanna, LEen_US
dc.date.accessioned2020-04-23T07:37:47Z
dc.date.available2020-04-23T07:37:47Z
dc.date.issued2019-03
dc.description.abstractWe report here the first case of pulmonary infection due to Mycobacterium kyorinense in a 55-year-old hypertensive woman treated for pulmonary tuberculosis earlier on two occasions. She presented with productive cough, intermittent episode of left-sided chest pain, loss of appetite, low-grade fever, and breathlessness. Sputum cultures revealed non-tuberculous mycobacteria (NTM). She remained persistently symptomatic with sputum cultures positive for acid-fast bacilli even after 6 months of treatment. Hence, a 16SrRNA gene amplification and sequencing were done that revealed M. kyorinense. Based on the guidelines of the American Thoracic Society, she was started on weight-based dosing of clarithromycin, levofloxacin, ethambutol, isoniazid and injection amikacin daily. The patient improved symptomatically and became culture-negative after 3 months of therapy with the above regimen and continued to be culture negative for 12 months of treatment. She continues to remain symptom-free without evidence of any clinical or bacteriological relapse.en_US
dc.identifier.affiliationsDepartment of HIV, ICMR-National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Clinical Research, ICMR-National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Bacteriology, ICMR-National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.citationSaranathan R, Padmapriyadarsini C, Sivaramakrishnan GN, Perumal BK, Kannayan S, Joseph B, Gopalan N, Hanna LE. Pulmonary Mycobacterium kyorinense disease: A case report and review of literature. Indian Journal of Medical Microbiology. 2019 Mar; 37(1): 127-131en_US
dc.identifier.issn0255-0857
dc.identifier.issn1998-3646
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/198852
dc.languageenen_US
dc.publisherIndian Association of Medical Microbiologistsen_US
dc.relation.issuenumber1en_US
dc.relation.volume37en_US
dc.source.urihttps://dx.doi.org/10.4103/ijmm.IJMM_19_94en_US
dc.subject16SrRNAen_US
dc.subjectnon-tuberculous mycobacteriaen_US
dc.subjectrifampicin resistanceen_US
dc.titlePulmonary Mycobacterium kyorinense disease: A case report and review of literatureen_US
dc.typeJournal Articleen_US
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