Blood stem cell transplantation: current concepts.

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dc.contributor.authorKamble, Ren_US
dc.contributor.authorRaju, G Men_US
dc.contributor.authorKumar, Len_US
dc.contributor.authorKochupillai, Ven_US
dc.date.accessioned1997-01-01en_US
dc.date.accessioned2009-05-27T07:44:14Z
dc.date.available1997-01-01en_US
dc.date.available2009-05-27T07:44:14Z
dc.date.issued1997-01-01en_US
dc.description55 references.en_US
dc.description.abstractMobilized peripheral blood haematopoietic progenitor cells are increasingly being used as against bone marrow (BM) transplants, following high dose chemotherapy and/or radiotherapy for the management of chemosensitive malignancies. Rapid haematopoietic reconstitution as evidenced by reduced duration of neutropaenia, fewer donor platelet infusions, shorter hospital stay and reduced cost of treatment are the advantages of this procedure. Reduced tumour cell contamination of mobilized blood compared to bone marrow however, has not been substantiated. Mobilization of lymphokine activated killer cells (LAK), use of blood stem cells (BSC) for allogeneic transplants and ex vivo expansion of the mobilized cells are emerging as the future areas for research. Addition of interleukin-3 (IL-3), stem cell factor (c-kit ligand) and PIXY-321 appear to open-up new vistas by enforcing trilineage and multilineage haematopoietic reconstitution.en_US
dc.description.affiliationDepartment of Medical Oncology, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationKamble R, Raju GM, Kumar L, Kochupillai V. Blood stem cell transplantation: current concepts. Indian Journal of Medical Research. 1997 Jan; 105(): 1-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/21871
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshBlood Specimen Collectionen_US
dc.subject.meshBone Marrow Transplantationen_US
dc.subject.meshHematopoietic Stem Cell Transplantationen_US
dc.subject.meshHumansen_US
dc.subject.meshRisk Factorsen_US
dc.titleBlood stem cell transplantation: current concepts.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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