IgG4‑related intraocular inflammation masquerading as ciliary body melanoma in a young girl.
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Date
2016-08
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Abstract
Immunoglobulin G4 (IgG4‑related diseases) affects various
tissues and organs of the human body. Orbital, adnexal, and
scleral inflammations were already reported in the medical
literature. To the best of our knowledge, we report the first
case of intraocular IgG4‑associated inflammatory mass in
the ciliary body mimicking as a melanoma in a 23‑year‑old
female from Northeast India. Characteristic histopathology,
immunohistochemistry in the tissue, protein chemistry, and
raised serum IgG4 were supportive for the diagnosis. As this
newly diagnosed disease has multi‑organ affection and little is
known about its pathogenesis particularly in eye and adnexa, the
present case will open many challenges in clinico‑pathological
diagnosis and research in the future.
Description
Keywords
Ciliary body, immunoglobulin G4‑related disease, immunohistochemistry, inflammation
Citation
Das Dipankar, Deka Panna, Verma Geeta, Kuri Ganesh Chandra, Bhattacharjee Harsha, Bharali Gayatri, Pandey Divya, Koul Akanksha, Das Bidisha, Deka Apurba. IgG4‑related intraocular inflammation masquerading as ciliary body melanoma in a young girl. Indian Journal of Ophthalmology. 2016 Aug; 64(8): 601-603.