Intraventricular metastasis from carcinoma breast masquerading as choroid plexus neoplasm: A case report

Simple item page
dc.contributor.authorDhamecha, Men_US
dc.contributor.authorSharma, Aen_US
dc.contributor.authorKamboj, Men_US
dc.contributor.authorPahwa, Sen_US
dc.contributor.authorPasricha, S.en_US
dc.date.accessioned2023-08-10T07:32:56Z
dc.date.available2023-08-10T07:32:56Z
dc.date.issued2022-09
dc.description.abstractMetastatic tumors in the brain represent the most common type of intracranial neoplasm, comprising 8–10% of all brain tumors. 30% of such tumors are primarily of breast origin in females. Brain parenchymal metastasis is the more common presentation. Intraventricular spread is rare, seen in less than 5% of cases in a metastatic scenario. Here, we report a case of 41-year-old female presenting with intraventricular brain metastasis in a follow-up case of carcinoma breast. Five years post-surgery, the patient presented with complaints of headache. On evaluation, magnetic resonance imaging (MRI) brain showed an intraventricular lesion in the fourth ventricle. She was operated on for the same and the biopsy revealed a tumor with a complex papillary pattern resembling choroid plexus papilloma. On immunohistochemistry (IHC), the tumor cells were positive for cytokeratin 7 (CK7), Epithelial membrane antigen (EMA), GATA3, and mammaglobin favoring a metastasis from breast origin. Hence, a possibility of brain metastasis should be kept in mind in patients presenting with solitary ventricular masses due to the lack of definite radiological characteristics in such locations and histological overlap. Also, organ-specific IHC is a must in today's evidence-based era as is reflected in our case.en_US
dc.identifier.affiliationsDepartment of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, Indiaen_US
dc.identifier.citationDhamecha M, Sharma A, Kamboj M, Pahwa S, Pasricha S.. Intraventricular metastasis from carcinoma breast masquerading as choroid plexus neoplasm: A case report. Indian Journal of Pathology & Microbiology. 2022 Sept; 65(3): 719-721en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223334
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber3en_US
dc.relation.volume65en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_92_21en_US
dc.subjectBrain metastasisen_US
dc.subjectbreasten_US
dc.subjectGATA-3en_US
dc.subjectIHCen_US
dc.subjectintraventricularen_US
dc.titleIntraventricular metastasis from carcinoma breast masquerading as choroid plexus neoplasm: A case reporten_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IJPM2022v65n3p719.pdf
Size:
1.48 MB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Pathology & Microbiology