Neuronal Remodeling and Dendritic Spines: A Review

Simple item page
dc.contributor.authorKumar, Adarshen_US
dc.contributor.authorTamta, Mamtaen_US
dc.contributor.authorHemlataen_US
dc.contributor.authorMaurya, Ram C.en_US
dc.date.accessioned2020-11-18T10:12:43Z
dc.date.available2020-11-18T10:12:43Z
dc.date.issued2019-01
dc.description.abstractThe neurons show remodeling in their dendritic arbor and spine/synapsenumber in many brain regions including the hippocampus, amygdala and the prefrontalcortex. The dendritic spine density is reported to be changed due to experiences andstressful conditions. The dendritic spines are the small protrusions arising from thedendritic shaft of the neurons. They have basic shapes as large mushroom spines, shortstubby spines and thin spines. The morphology of spines changes rapidly in response tovarious stimuli that may be internal such as hormones and external such as environmentalchanges. Dendritic spine density plays a major role in classification of principal neuronsi.e. multipolar and pyramidal neurons. The principal neurons may be classified as sparselyspinous, moderately spinous and heavily spinous on the basis of density of spine over thedendritic branches. In response to environment dendritic remodeling takes place in theform of spine shapes, spine turnover and spine density etc. Synaptic plasticity primarilytakes place in dendritic spines and enriched environment have positive effect while socialisolation have negative effect on synapse formation. Exposure of animals to environmentalcomplexity may improve the learning and memory by providing adaptive changes in thedendritic spine density.en_US
dc.identifier.affiliationsDepartment of Zoology (DST-FIST Sponsored), Kumaun University, S.S.J. Campus, Almora, Uttarakhand, Indiaen_US
dc.identifier.citationKumar Adarsh, Tamta Mamta, Hemlata, Maurya Ram C.. Neuronal Remodeling and Dendritic Spines: A Review. Journal of Biological Engineering Research and Review. 2019 Jan; 6(1): 29-36en_US
dc.identifier.issn2349-3232
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/214156
dc.languageenen_US
dc.publisherSB Publicationsen_US
dc.relation.issuenumber1en_US
dc.relation.volume6en_US
dc.source.urihttps://biologicalengineering.in/gallery/19-06-01-05.pdfen_US
dc.subjectDendritic spinesen_US
dc.subjectEnriched environmenten_US
dc.subjectPlasticityen_US
dc.subjectMorphology;Learningen_US
dc.subjectMemoryen_US
dc.titleNeuronal Remodeling and Dendritic Spines: A Reviewen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
jbbr2019v6n1p29.pdf
Size:
1020.53 KB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Biological Engineering Research and Review