Etiologic study of primary congenital hypothyroidism.

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dc.contributor.authorSeeherunvong, Ten_US
dc.contributor.authorChuresigaew, Sen_US
dc.date.accessioned2009-05-27T20:24:00Z
dc.date.available2009-05-27T20:24:00Z
dc.date.issued1998-09-16en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe underlying causes of 35 children with primary congenital hypothyroidism at the Children's Hospital were studied. There were 21 girls and 14 boys. Serum T4 and TSH level, 24 hours 131I uptake, and technetium-99m thyroid scintigraphy were performed after discontinuation of synthetic thyroid hormone for 4-6 weeks. Athyrosis was the most common cause and accounted for forty-three per cent of the patients. Twenty per cent of the patients had thyroid hypoplasia. Ectopic thyroid was found in thirty-three per cent of the patients. Only a patient whose diagnosis was organification defect had slightly enlarged thyroid gland, high retention of 131I and positive perchlorate discharge test. Onset of symptoms before 9 months of age may be helpful for distinguishing between lingual thyroid and the others. Serum T4 level less than 2 micrograms/dL was observed to be more common in athyrosis and lingual thyroid groups than thyroid hypoplasia group.en_US
dc.description.affiliationDepartment of Medical Services, Children's Hospital, Bangkok, Thailand.en_US
dc.identifier.citationSeeherunvong T, Churesigaew S. Etiologic study of primary congenital hypothyroidism. Journal of the Medical Association of Thailand. 1998 Sep; 81(9): 653-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42926
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCongenital Hypothyroidismen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypothyroidism --blooden_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshThyrotropin --blooden_US
dc.subject.meshThyroxine --blooden_US
dc.titleEtiologic study of primary congenital hypothyroidism.en_US
dc.typeJournal Articleen_US
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