Clinical trials of broad spectrum anthelmintics against soil-transmitted helminthiasis.
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1980-12-01
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Abstract
Clinical trials on the three broad spectrum anthelmintics against trichuriasis, ascariasis and hookworm infection were carried out in a rural community in Irosin, Sorsogon. Flubendazole (Fluvermal) appears to be a promising drug against trichuriasis particularly when periodic mass treatment of a community is carried out. Mebendazole (Antiox) also appears to be promising given as single dose during mass treatment of soil-transmitted helminthiasis. As shown in previous studies, oxantel-pyrantel (Quantrel) should be given at 15 mg/kg body weight at 12-hour intervals or 20 mg/kg body weight single dose rather than 10 mg/kg body weight in a single dose when treating trichuriasis.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Cabrera BD, Valdez EV, Go TG. Clinical trials of broad spectrum anthelmintics against soil-transmitted helminthiasis. The Southeast Asian Journal of Tropical Medicine and Public Health. 1980 Dec; 11(4): 502-6