DA Study of the Clinico-demographic Profile and Clinical Outcomes of COVID-19 Patients in a Tertiary Care Hospital of India
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Date
2024-12
Journal Title
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Publisher
THE INDIAN MEDICAL ASSOCIATION
Abstract
Background : The SARS-CoV-2-induced COVID-19 pandemic has presented substantial challenges to healthcare systems across the globe. This study aimed to investigate the clinico-demographic profile and clinical outcomes of COVID-19 patients in a tertiary care hospital in Barak Valley, Assam, India. Methodology : A retrospective, single-center, hospital-based cross-sectional study was conducted, focusing on patients with laboratory-confirmed COVID-19 admitted between July, 2020 and December, 2020. Results : A total of 353 patients were analyzed with 69% being male and 31% female. Patients were classified into three severity groups: mild, moderate and severe. The mean ages in the mild, moderate and severe groups were 41.58 years, 57.70 years and 59.54 years, respectively. Cachar district accounted for the majority of patients (68.83%), followed by Karimganj district (18%) and Hailakandi district (10%). The common presenting complaints included fever, cough and dyspnoea. Co-morbidities were present in 61.76% of patients, with diabetes and hypertension being the most prevalent. Pulmonary comorbidities showed a strong association with increased mortality rates. Vital signs and laboratory parameters worsened with disease severity with neutrophils increasing and lymphocytes decreasing. Ferritin and LDH levels also increased with severity, reflecting disease progression. Treatment involved remdesivir and convalescent plasma therapy, with the combination showing better outcomes compared to individual therapies. Conclusion : Overall, the study provides valuable insights into the unique challenges and characteristics of COVID- 19 patients in the low HDI region of Barak Valley, Assam. The findings can aid in targeted public health interventions, resource allocation and equitable healthcare delivery, ultimately mitigating the impact of the disease and improving patient outcomes in the region. However, the study has certain limitations and further prospective multi-center studies are needed to validate and expand upon these findings.
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Keywords
COVID-19, Co-morbidity, Clinico-demographic, Mortality, Treatment
Citation
Nath Rupankar, Sutradhar Deepannita, Thakuria Riturag . DA Study of the Clinico-demographic Profile and Clinical Outcomes of COVID-19 Patients in a Tertiary Care Hospital of India. Journal of the Indian Medical Association. 2024 Dec; 122(12): 23-28