Laboratory techniques for diagnosis of chlamydial infections of the eye.

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dc.contributor.authorBaveja, U Ken_US
dc.contributor.authorHiranandani, M Ken_US
dc.contributor.authorTalwar, Pen_US
dc.contributor.authorSen, D Ken_US
dc.date.accessioned1997-09-18en_US
dc.date.accessioned2009-06-01T19:18:04Z
dc.date.available1997-09-18en_US
dc.date.available2009-06-01T19:18:04Z
dc.date.issued1997-09-18en_US
dc.description.abstractGiemsa and fluorescence antibody (FA) staining were used to diagnose patients clinically suspected to be suffering from trachoma. A total of 52 controls i.e. individuals with refractive errors and no clinical trachoma and 173 cases suffering from different stages of trachoma were studied. FA was found to be 2.52 times more sensitive in confirming the presence of Chlamydia trachomatis compared to Giemsa staining. 28/52 (53.8%) and 4/52 (7.,69%) controls were also positive by FA and Giemsa staining, respectively, indicating sub-clinical infection without symptoms. Post treatment staining with both methods revealed that clinical cure of trachoma did not necessarily mean the absence of Chlamydia trachomatis in the conjunctival smears. As a corollary it can be deduced that mere presence of Chlamydia trachomatis in conjunctival epithelial cells may not cause clinical trachoma, certain host factors (local immunity etc.) may play an important role in clinical disease.en_US
dc.description.affiliationNational Institute of Communicable Diseases, Sham Nath Marg, Delhi.en_US
dc.identifier.citationBaveja UK, Hiranandani MK, Talwar P, Sen DK. Laboratory techniques for diagnosis of chlamydial infections of the eye. Journal of Communicable Diseases. 1997 Sep; 29(3): 247-53en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/112853
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshStaining and Labelingen_US
dc.subject.meshTrachoma --diagnosisen_US
dc.titleLaboratory techniques for diagnosis of chlamydial infections of the eye.en_US
dc.typeJournal Articleen_US
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